Heart Failure
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Heart Failure
The prevalence of heart failure (HF) continues to increase over time1 and affects >60 million people each year2.
Therefore, being aware of the latest data in the HF space and different treatment options is important in order to be able to apply findings to clinical practice when making treatment decisions for patients with type 2 diabetes mellitus (T2DM) and cardiovascular disease, especially HF.
This section is supported by a grant from the Boehringer Ingelheim & Eli Lilly and Company Alliance
Content on this section was partly provided by Boehringer Ingelheim. For any follow up questions please contact your local Boehringer Ingelheim representative.
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This review summarizes the latest developments in our understanding of the role of the innate and adaptive immune systems in the pathogenesis of heart failure and highlights the results of phase III clinical trials of therapies targeting...
Adamo L, Rocha-Resende C, Prabhu SD, Mann DL. Nat Rev Cardiol 2020;17:269–85. -
This article provides an approach for primary care physicians to managing peripheral oedema in people known to have heart failure in the community and the article includes a recap of the best available evidence.
Bromage D, Mayhew J, Sado D. BMJ 2020;369:m2099. -
The current pandemic coronavirus SARS-CoV-2 infects a wide age group but predominantly elderly individuals, especially men and those with cardiovascular disease. Recent reports suggest an association with use of renin–angiotensin–aldosterone...
Sama IE, Ravera A, Santema BT, et al. Eur Heart J 2020;41:1810–7. -
The authors carried out a systematic review and meta-analysis of randomised, placebo-controlled, cardiovascular outcome trials of SGLT2i in patients with type 2 diabetes.
Zelniker TA, Wiviott SD, Raz I, et al. Lancet. 2019;393:31–9.
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Review articles
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Verma S, McMurray JJV. Diabetologia. 2018;61:2108–17.
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Sattar N, McLaren J, Kristensen SL, et al. Diabetologia. 2016;59:1333–9.
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Verma S, McMurray JJV, Cherney DZI. JAMA Cardiol. 2017;2:939–40.
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Gevaert AB, Boen JRA, Segers VF, Van Craenenbroeck EM. Front Physiol. 2019;10:638.
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Cefalo CMA, Cinti F, Moffa S, et al. Cardiovasc Diabetol. 2019;18:20.
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Systematic Analysis
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Guidelines
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Clinical Case Study
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Wiviott SD, Raz I, Mosenzon O, et al. N Engl J Med 2019; 380:347–57.
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Press Announcements
Study Design
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1.Heart disease and stroke statistics-2020 update: a report from the American Heart Association
Virani SS, Alonso A, Benjamin EJ, et al. Circulation 2020;141:e139-e596.
https://doi.org/10.1161/CIR.0000000000000757
2. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016
GBD 2016 Disease and Injury Incidence and Prevalence Collaborators. Lancet 2017;390:1211-59.
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