Roxana Mehran

Roxana Mehran

Professor of Medicine, Cardiology and Professor of Population Health Science and Policy

MD

Mount Sinai Hospital, New York City, US

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Biography

Roxana Mehran is an internationally recognised interventional cardiologist and clinical researcher based in New York, United States. She has spent much of her professional career at the Icahn School of Medicine at Mount Sinai and Mount Sinai Hospital, where she has become a leading figure in cardiovascular clinical trials, interventional cardiology, and outcomes research. Her work is widely noted for its focus on improving patient outcomes, advancing evidence-based care, and promoting sex-specific research in cardiovascular medicine.

 

Academic History

Professor Mehran pursued her medical education and postgraduate training in internal medicine and cardiology, followed by subspecialty training in interventional cardiology. Her academic career has been closely aligned with Mount Sinai, where she has advanced through senior academic ranks.

She currently holds appointments as Professor of Medicine (Cardiology) and Professor of Population Health Science and Policy at the Icahn School of Medicine at Mount Sinai. Her academic work integrates clinical medicine, population health, and rigorous clinical trial methodology, reflecting her commitment to translating research findings into real-world cardiovascular care.

 

Career Overview

Professor Mehran serves as Director of Interventional Cardiovascular Research and Clinical Trials at The Zena and Michael A. Weiner Cardiovascular Institute at Mount Sinai Hospital. In this role, she has led the development of a globally respected data and clinical coordination centre that supports large, multicentre, multinational cardiovascular clinical trials. Under her leadership, this centre has become a major contributor to studies aimed at improving outcomes and quality of life for patients undergoing interventional cardiovascular procedures.

Her research has had a particular emphasis on antithrombotic therapy, including anticoagulation and antiplatelet regimens following angioplasty and transcatheter valve replacement. In parallel, she has been a prominent advocate for the collection, analysis, and interpretation of sex-specific data in cardiovascular clinical trials, helping to address longstanding gaps in evidence for women with cardiovascular disease.

Professor Mehran has played a significant role in cardiovascular publishing and professional leadership. She serves on the editorial boards of multiple leading peer-reviewed journals, including the Journal of the American College of Cardiology, Circulation, and Circulation Research. She is also a member of the editorial board of Interventional Cardiology: Reviews, Research, Resources.

In addition to her editorial work, she holds numerous leadership positions within major professional organisations. She serves on the board of trustees of the Society of Cardiac Angiography and Interventions, is a member of the Program Committee for the American Heart Association Scientific Sessions, and sits on the board of directors for Harboring Hearts. She is also Program Chair for the Society of Cardiac Angiography and Interventions’ Women in Innovations Initiative. Beyond these roles, she serves as Chief Scientific Officer of the Clinical Trials Center at the Cardiovascular Research Foundation.

 

Career Timeline

  • Completion of medical education and postgraduate training in cardiology and interventional cardiology
  • Appointment to faculty positions at the Icahn School of Medicine at Mount Sinai
  • Named Professor of Medicine (Cardiology) and Professor of Population Health Science and Policy, Mount Sinai
  • Appointed Director of Interventional Cardiovascular Research and Clinical Trials, Mount Sinai Hospital
  • Development of a global cardiovascular data and clinical coordination centre
  • Assumption of senior leadership roles in major cardiovascular societies and journals
  • Appointment as Chief Scientific Officer, Clinical Trials Center, Cardiovascular Research Foundation

 

Recognition

Professor Mehran is widely regarded as a leading authority in interventional cardiology and cardiovascular clinical trials. Her work has significantly influenced contemporary practice in antithrombotic therapy and trial design, particularly in the context of complex coronary and structural heart interventions. She is frequently invited to speak at major international cardiology meetings and is recognised for her leadership in advancing sex-specific cardiovascular research and mentoring the next generation of clinician-scientists.

 

Areas of Speciality

  • Interventional Cardiology
  • Cardiovascular Clinical Trials
  • Anticoagulation and Antiplatelet Therapy
  • Angioplasty and Transcatheter Valve Procedures
  • Sex-Specific Cardiovascular Outcomes
  • Population Health in Cardiology

 

Sources

Read more

Media

Broadcast

Intervention
Transcatheter Interventions Online 2026 - Day Two

Nicolas M Van Mieghem, David Hildick-Smith, Roxana Mehran , et al

Broadcast

Intervention
Transcatheter Interventions Online 2026 - Day One

Nicolas M Van Mieghem, David Hildick-Smith, Roxana Mehran , et al

Women in Cardiology: Small in Number, Large in Impact

Roxana Mehran, Mirvat Alasnag, Julia Grapsa, et al

Watch time: 32m 27s

Broadcast

Intervention
Transcatheter Interventions Online 2025 - Day Three

Nicolas M Van Mieghem, David Hildick-Smith, Roxana Mehran , et al

Broadcast

Intervention
Transcatheter Interventions Online 2025 - Day Two

Nicolas M Van Mieghem, David Hildick-Smith, Roxana Mehran , et al

Broadcast

Intervention
Transcatheter Interventions Online 2025 - Day One

Nicolas M Van Mieghem, David Hildick-Smith, Roxana Mehran , et al

EuroPCR 24: The ABILITY Study

Roxana Mehran

Watch time: 3m 59s
EuroPCR 24: Ancillary SMART Trial Analyses

Roxana Mehran

Watch time: 5m 19s

Antoinette Neylon, Roxana Mehran, Martin Swaans, et al

Watch time: 45m 15s (8 videos)

Broadcast

Intervention
Transcatheter Interventions Online 2024 - Day Three

Nicolas M Van Mieghem, Kendra J Grubb, David Hildick-Smith , et al

Broadcast

Intervention
Transcatheter Interventions Online 2024 - Day Two

Nicolas M Van Mieghem, Kendra J Grubb, David Hildick-Smith , et al

Broadcast

Intervention
Transcatheter Interventions Online 2024 - Day One

Nicolas M Van Mieghem, Kendra J Grubb, David Hildick-Smith , et al

Uniform Pathway of Care for OHCA: Key Messages from the BCIS Statement

Nick Curzen, Tom Keeble, Peter O’Kane, et al

Watch time: 35m 11s

Nicolas M Van Mieghem, Holger Thiele, Azeem Latib, et al

Watch time: 14h 38m 12s (23 videos)

Roxana Mehran, Pascal Vranckx, Marco Valgimigli, et al

Watch time: 1h 27m 41s (4 videos)

Broadcast

Intervention
Transcatheter Interventions Online 2023 - Day Three

Nicolas M Van Mieghem, Roxana Mehran, Holger Thiele , et al

Broadcast

Intervention
Transcatheter Interventions Online 2023 - Day Two

David Hildick-Smith, Ajay J Kirtane, Nicolas M Van Mieghem , et al

Broadcast

Intervention
Transcatheter Interventions Online 2023 - Day One

Nicolas M Van Mieghem, Azeem Latib, Kendra J Grubb , et al

Robert F Storey, Roxana Mehran, Dominick J Angiolillo, et al

Watch time: 1h 45m 35s (7 videos)
Transcatheter Interventions Online 2022 - On Demand

Joost Daemen, Roxana Mehran, David Hildick-Smith, et al

USC 21 Discussion: Women In Cardiology

Roxana Mehran, Shrilla Banerjee, Burt Cohen, et al

Watch time: 32m 29s

Broadcast

Intervention
Transcatheter Interventions Online 2022 - Day 3

Nicolas M Van Mieghem, Holger Thiele, Roxana Mehran , et al

Broadcast

Intervention
Transcatheter Interventions Online 2022 - Day 2

Nicolas M Van Mieghem, Holger Thiele, Roxana Mehran , et al

Broadcast

Intervention
Transcatheter Interventions Online 2022 - Day 1

Nicolas M Van Mieghem, Roxana Mehran, Kendra J Grubb , et al

Nicolas M Van Mieghem, Kendra J Grubb, David Hildick-Smith, et al

Watch time: 14h 48m 39s (16 videos)

Dominick J Angiolillo, Robert F Storey, Roxana Mehran, et al

Watch time: 1h 28m 48s (5 videos)
TCT Connect 2020: The XIENCE 90/28 Trials

Roxana Mehran

Watch time: 8m 43s

Kurt Huber, Davide Capodanno, Roxana Mehran, et al

Watch time: 1h 1m 15s (5 videos)

Nicolas M Van Mieghem, Kendra J Grubb, Holger Thiele, et al

Watch time: 11h 25m 16s (11 videos)
Mending the broken house of cardiology with Roxana Mehran

Ankur Kalra, Roxana Mehran,

Listen time: 40m 56s
CRT 2020: Should we drop aspirin monotherapy?

Roxana Mehran

Watch time: 6m 21s
AHA 2019: Clinical Data Update on Antithrombotics

Marc P Bonaca, Roxana Mehran

Watch time: 17m 29s
AHA 2019: Clinical Data Update on TWILIGHT and TWILIGHT-ACS

Marc P Bonaca, Roxana Mehran

Watch time: 5m 5s
AHA 2019: Clinical Data Update on GALILEO

Roxana Mehran, Marc P Bonaca

Watch time: 7m 49s
AHA 2019: Clinical Data Update on ISCHEMIA

Marc P Bonaca, Roxana Mehran

Watch time: 7m 49s
AHA 2019 Discussion: Women in Cardiology

Harriette Van Spall, Roxana Mehran

Watch time: 10m 32s
ESC 2018: The DIAB8 Study - Prof Roxana Mehran

Roxana Mehran

Watch time: 4m 3s

Articles by Roxana Mehran, Professor of Medicine, Cardiology and Professor of Population Health Science and Policy

Artificial Intelligence – Advisory or Adversary?

Johny Nicolas, Nicholas L Pitaro, Birgit Vogel, et al

Published:

Citation: Interventional Cardiology 2023;18:e17.

DOI:

https://doi.org/10.15420/icr.2022.22
Sex-based Differences in Percutaneous Coronary Intervention Outcomes in Patients with Ischaemic Heart Disease

Antonia Sambola, Bruno García Del Blanco, Vijay Kunadian, et al

Published:

Citation: European Cardiology Review 2023;18:e06.

DOI:

https://doi.org/10.15420/ecr.2022.24
British Cardiovascular Interventional Society Consensus: a Huge Step Towards Standardised Care for Out-of-hospital Cardiac Arrest in the UK

Marko Noc, Roxana Mehran,

Published:

Citation: Interventional Cardiology 2022;17:e17.

DOI:

https://doi.org/10.15420/icr.2022.25
The Final Word: Current Strategies for the Lifetime Management of Patients with Aortic Valve Stenosis

Anne H Tavenier, Johny Nicolas, Roxana Mehran, et al

Published:

Citation: US Cardiology Review 2022;16:e13.

DOI:

https://doi.org/10.15420/usc.2022.07
TWILIGHT: A Randomized Trial of Ticagrelor Monotherapy Versus Ticagrelor Plus Aspirin Beginning at 3 Months in High-risk Patients Undergoing Percutaneous Coronary Intervention

Johny Nicolas, Usman Baber, Roxana Mehran, et al

Published:

Citation: US Cardiology Review 2020;14:e04.

DOI:

https://doi.org/10.15420/usc.2019.02
Non-vitamin K Antagonist Oral Anticoagulant After Acute Coronary Syndrome: Is There a Role?

Paul Guedeney, Birgit Vogel, Roxana Mehran, et al

Citation: Interventional Cardiology Review 2018;13(2):93–8.

DOI:

https://doi.org/10.15420/icr.2018:5:2
Guest Editorial: A Brave New World for Non-vitamin K Antagonist Oral Anticoagulants: Have We seen the Last of Warfarin?

Michela Faggioni, Michael C Gibson, Roxana Mehran, et al

Citation: US Cardiology Review 2017; 11(1):37–8

DOI:

https://doi.org/10.15420/usc.2017:6:1.GE
Preventing Contrast-induced Renal Failure: A Guide

Michela Faggioni, Roxana Mehran,

Citation: Interventional Cardiology Review 2016;11(2):98–104

DOI:

https://doi.org/10.15420/icr.2016:10:2
Cre8™ Unique Technology in Challenging Daily Practice

David Antoniucci, Roxana Mehran, Giuseppe DeLuca, et al

Citation: Interventional Cardiology Review 2014;9(3):180–3

DOI:

https://doi.org/10.15420/icr.2014.9.3.180
Contrast-induced Nephropathy in a High-risk Patient Population

Adriano Caixeta, Eugenia Nikolsky, Roxana Mehran, et al

Citation: Interventional Cardiology 2008;3(1):10-5

DOI:

https://doi.org/10.15420/icr.2008.3.1.10
The Role of New Antiplatelet Agents in Percutaneous Coronary Intervention

Benjamin Galper, Roxana Mehran,

Citation: Interventional Cardiology 2009;4(1):81-4

DOI:

https://doi.org/10.15420/icr.2009.4.1.81