Persistent Atrial Fibrillation Using Arctic Front™ Cardiac Cryoablation System


Arctic FrontTM cryoballoon ablation of atrial fibrillation has radically altered the landscape of electrophysiology, providing highly reproducible results for pulmonary vein isolation (cryo-PVI), and cryoablation with Arctic FrontTM cryoballoon is now routinely considered as equivalent in efficacy to radiofrequency ablation. This efficacy and safety profile of cryo-PVI has also been translated across to our persistent AF patients, driven by the realisation that a PVI procedure provides an equivalent or better outcome than including empiric lines/fractionated electrogram ablation opened. This has greatly expanded the patient base for whom this could be a useful treatment. As we expand the population of patients who are ideally treated with cryoablation, and increase the numbers of centres undertaking the procedure, we must remain mindful of best practices and incremental improvements in the field.  


We very much hope you enjoy the featured articles in this collection and find them useful in the delivery of best-practice treatment for your patients.


Dr Malcolm Finlay

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Section Advisor

Dr Malcolm Finlay, Consultant Cardiologist, Barts Heart Centre

Arctic Front Family of cryoballoons is the first FDA-approved ablation catheter for the treatment of Persistent AF in the US

The Persistent Atrial Fibrillation using Cryoballoon section is supported by Medtronic

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Cryoablation or drug therapy for initial treatment of atrial fibrillation

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Yorgun H, Canpolat U, Okşul M, et al. Europace 2019;21;11:1653-1662.

12 Month Efficacy, Safety, Symptoms And Improved Quality Of Life Post Arctic Front Advance Cryoballoon Ablation In Persistent AF Patients

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Point‐by‐Point Radiofrequency Ablation Versus the Cryoballoon or a Novel Combined Approach: A Randomized Trial Comparing 3 Methods of Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation (The Cryo Versus RF Trial)

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Cryoballoon Versus Open Irrigated Radiofrequency Ablation in Patients With Paroxysmal Atrial Fibrillation: The Prospective, Randomized, Controlled, Noninferiority FreezeAF Study

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Safety and efficacy outcomes of left atrial posterior wall isolation compared to pulmonary vein isolation and pulmonary vein isolation with linear ablation for the treatment of persistent atrial fibrillation

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Quality of life after catheter and minimally invasive surgical ablation of paroxysmal and early persistent atrial fibrillation: results from the SCALAF trial

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Outcomes of cryoballoon or radiofrequency ablation in symptomatic paroxysmal or persistent atrial fibrillation

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The Hot and the Cold: Radiofrequency Versus Cryoballoon Ablation for Atrial Fibrillation

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