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Hypertension is the most common modifiable risk factor for cardiovascular disease and death, and lowering blood pressure with antihypertensive drugs reduces target organ damage and prevents cardiovascular disease outcomes.

Most hypertensive patients will need a combination of antihypertensive agents to achieve the therapeutic goals. Recent guidelines recommend initiating treatment with two drugs in those patients with a systolic blood pressure >20 mmHg and/or a diastolic blood pressure >10 mmHg above the goals, and in those patients with high cardiovascular risk. In addition, approximately 25% of patients will require three antihypertensive agents to achieve the therapeutic targets.

Articles

Angiotensin-receptor Blocker Therapy—Chronic Kidney Disease and Diabetes

Citation:

US Cardiology 2006;3(2):32–4

Chronic Thromboembolic and Pulmonary Arterial Hypertension Share Acute Vasoreactivity Properties

Citation:

European Cardiovascular Disease 2006;2(2):1–4

The Role of Oral Vasoactive Agents in the Treatment of Pulmonary Arterial Hypertension

Citation:

US Cardiology 2006;3(1):39–42

Evaluation and Diagnosis of Pulmonary Arterial Hypertension

Citation:

US Cardiology 2006;3(1):30–2