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AHA 22 Late-Breaker Discussion: The Diuretic Comparison Project

Published: 16 Dec 2022

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AHA 2022 — Late-breaker Host, Dr Harriette Van Spall (McMaster University, CA) met investigator, Dr Areef Ishani (Minneapolis VA Health Care System, US) to discuss the The Diuretic Comparison Project (DCP) (NCT02185417).

The aim of this study was to compare two thiazide-type diuretics, chlorthalidone and hydrochlorothiazide in 13523 patients over age 65 with hypertension.

Published in The New England Journal of Medicine, this pragmatic study showed that patients who received chlorthalidone did not have a lower occurrence of major cardiovascular outcome events or non–cancer-related deaths than patients who received hydrochlorothiazide.

Recorded remotely from AHA 2022. 

Editor: Mirjam Boros
Video Specialist: Oliver Miles and Dan Brent