Andrew SP Sharp

Andrew SP Sharp

Professor of Cardiology

MD FRCP MB MBBCh

University College Dublin and The Mater Misericordiae Hospital, Dublin, IE

  • X
  • Radcliffe

Biography

Andrew Sharp qualified from Edinburgh Medical School in 1998 and subsequently pursued an MD postgraduate research degree at the University of Edinburgh. His doctoral research focused on the hypertensive heart, establishing a foundation for his ongoing clinical and academic interest in hypertension and cardiovascular disease.

 

Clinical Training & Early Career

Dr Sharp completed his early clinical training at the Royal Infirmary of Edinburgh before moving to London for senior clinical training at the hospitals of Imperial College London. He then undertook the prestigious Milan-Imperial Interventional Cardiology Fellowship programme, which included a year in Milan at San Raffaele and Columbus Hospitals, where he trained under leading experts in interventional cardiology. This combination of UK and international training shaped his expertise in complex coronary interventions and device-based therapies.

 

Career Progression

  • In 2011 he was appointed Consultant Cardiologist at the Royal Devon and Exeter Hospital
  • In 2018 he became Honorary Associate Professor at the University of Exeter
  • In summer 2019, he moved to the University Hospital of Wales in Cardiff
  • More recently he has been appointed as Professor of Cardiology at University College Dublin and at the Mater Misericordiae Hospital, Dublin, Ireland
  • Dr Sharp also serves as Deputy Editor (Development) of the journal Interventional Cardiology: Reviews, Research, Resources (ICR3)

 

Research Interests & Expertise

  • Dr  Sharp’s current research and clinical interests include
  • Device‑based treatments for hypertension (particularly catheter‑based and interventional treatments)
  • Treatment of pulmonary embolism through catheter‑based interventions
  • Intracoronary imaging and coronary physiology to better assess and manage chest pain and coronary artery disease
  • Complex angioplasty and stenting for coronary artery disease, including use of advanced imaging and physiology‑guided intervention techniques, and also CT coronary angiography

 

Major Contributions & Roles

  • He has been a steering‑committee member and investigator in major clinical trial programmes of renal denervation — notably the ultrasound‑based RADIANCE programme, and served as global co‑principal investigator for the RF‑based SPYRAL DYSTAL trial
  • He led the UK Renal Denervation Affiliation and published the largest investigator‑led registry study of RDN at the time
  • His group has also generated preclinical data supporting the durability of renal denervation and contributed to European and international consensus statements on the role of RDN in hypertension
  • In the field of coronary artery disease, he has been involved in numerous clinical trials and registries assessing intracoronary physiology and intravascular imaging (e.g., IVUS, fractional flow reserve) to optimise interventions
  • Since 2012 he has been principal investigator in over 30 ethically approved research trials, with a substantial publication record, and is frequently invited to lecture at national and international conferences in areas including hypertension, coronary disease, and pulmonary embolism

 

Areas of Speciality

  • Resistant hypertension — pharmacological and interventional management (notably renal denervation)
  • Pulmonary embolism — catheter‑based intervention and device treatments
  • Coronary artery disease — advanced angioplasty and stenting, guided by intracoronary imaging and physiology
  • CT coronary angiography and non‑invasive imaging of coronary disease where relevant

 

References

  1. https://nipc.ie/national-prevention-conference-speaker-bios-2024/
  2. https://www.radcliffemedicaleducation.org/author/prof-andrew-sharp
  3. https://www.radcliffecardiology.com/authors/andrew-sp-sharp?language_content_entity=en
  4. https://simpleeducation.co/moments/919
  5. https://kclpure.kcl.ac.uk/portal/files/79229521/Renal_artery_sympathetic_denervation_SHARP_accepted_29Dec2015_epub_22Jan2016_GOLD_VoR_CCBY.pdf
  6. https://pmc.ncbi.nlm.nih.gov/articles/PMC11139244/


 

Read more

Media

Andrew SP Sharp, Mantas Buitkus, Gilles Lemesle

Watch time: 1h 3m 43s (4 videos)

Broadcast

Intervention

Vascular Disease and Surgery
Pulmonary Embolism Management

Andrew SP Sharp, Mantas Buitkus, Gilles Lemesle

Watch time: 1h 3m 44s

Andrew SP Sharp, Joost Daemen

Cost Effectiveness Analysis of Renal Denervation

Andrew SP Sharp

Watch time: 5m 17s
Science of Renal Denervation Technology

Andrew SP Sharp, Stefan Tunev

Watch time: 20m 50s

Andrew SP Sharp, Atul Pathak, Felix Mahfoud, et al

Watch time: 1h 17s

Broadcast

Intervention

MI/ACS
Precision Diagnostics in LM Bifurcation Disease

José M de la Torre Hernández, Tamara García Camarero, Andrew SP Sharp , et al

Watch time: 1h 39m 31s
Part 2: PoTS sub-types (neuropathic/hyperadrenergic/volume dysregulation etc…)

Andrew SP Sharp, Melvin D Lobo, Lesley Kavi, et al

Watch time: 12m 39s
PART 3: Comorbidities in PoTS (Breathing/Gut/GUS/Neuro)

Andrew SP Sharp, Melvin D Lobo, Lesley Kavi, et al

Watch time: 15m 49s
Part 4: Non-pharmacological management of PoTS

Andrew SP Sharp, Melvin D Lobo, Lesley Kavi, et al

Watch time: 11m 58s
Part 5: Drug therapy of PoTS: Rhythm control, Circulatory control

Andrew SP Sharp, Melvin D Lobo, Lesley Kavi, et al

Watch time: 11m 47s
Part 6: The Future of PoTS - Gall

Andrew SP Sharp, Melvin D Lobo, Nick Gall, et al

Watch time: 14m 22s
Part 1: PoTS definition, epidemiology & diagnosis

Andrew SP Sharp, Melvin D Lobo, Lesley Kavi, et al

Watch time: 16m 41s

Broadcast

Intervention

Prevention & Chronic Conditions
The Science of Radiofrequency Renal Denervation

Stefan Tunev, Andrew SP Sharp,

Watch time: 1h 12m 55s
The science of renal denervation - Part 1

Stefan Tunev, Andrew SP Sharp

Watch time: 30m 24s

Andrew SP Sharp, Atul Pathak, Roland E Schmieder, et al

Watch time: 1h 29m 27s (3 videos)

Broadcast

Imaging & Diagnostics
The Angiogram Is Not Enough

Andrew SP Sharp,

Watch time: 1h 10s
TCT 2019: RF renal denervation - Prof Andrew Sharp

Andrew SP Sharp

Watch time: 9m 14s
ESC 2018: Rationale For New Treatment Options For Intermediate

Nicolas Meneveau, Andrew SP Sharp, Adriaan Kraaijeveld, et al

Watch time: 14m 32s

Broadcast

Prevention & Chronic Conditions

Intervention
Can Renal Denervation Benefit Patients with Hypertension?

Andrew SP Sharp, Indranil Dasgupta, Felix Mahfoud , et al

Watch time: 1h 13m 4s
ESC 2018: Rationale for New Treatment Options for Intermediate-High Risk PE Patients

Nicolas Meneveau, Andrew SP Sharp, Adriaan Kraaijeveld, et al

Watch time: 19m 4s
New Treatment Options For Intermediate-High Risk PE

Nicolas Meneveau, Andrew SP Sharp, Adriaan Kraaijeveld, et al

Watch time: 27m 16s
ESC 2018: Rationale For New Treatment Options For Intermediate-High Risk PE Patients

Nicolas Meneveau, Andrew SP Sharp, Adriaan Kraaijeveld, et al

Watch time: 14m 32s
ESC 2018: Rationale For New Treatment Options For Intermediate-High Risk PE Patients

Nicolas Meneveau, Andrew SP Sharp, Adriaan Kraaijeveld, et al

Watch time: 14m 32s
ESC 2018: Rationale For New Treatment Options For Intermediate-High Risk PE Patients

Andrew SP Sharp, Adriaan Kraaijeveld, Nicolas Meneveau, et al

Watch time: 14m 32s
Symposium at ESC Congress 2018 sponsored by EKOS Corporation

Nicolas Meneveau, Andrew SP Sharp, Adriaan Kraaijeveld, et al

Watch time: 5m 49s

Broadcast

Imaging & Diagnostics

Intervention
Use of Intravascular Ultrasound (IVUS) in Ambiguous Angiograms

Robert Gerber, Andrew SP Sharp,

Watch time: 58m 14s
ESC 2017: Catheter-Based Renal Denervation

Andrew SP Sharp

Watch time: 6m 42s
Optimum Duration Of Acoustic Pulse Thrombolysis Procedure

Andrew SP Sharp

Watch time: 8m 38s

Andrew SP Sharp, Takashi Akasaka, Carlo Di Mario, et al

Simon Kennon, Stephan Achenbach, Sergio Baptista, et al

Image

Simon Kennon, Stephan Achenbach, Sergio Baptista, et al

Watch time: 17m 54s

Simon Kennon, Stephan Achenbach, Sergio Baptista, et al

EuroPCR 2015: Update on iFR and FFR

Simon Kennon, Andrew SP Sharp

Watch time: 13m 53s
EuroPCR 2015: Renal Denervation: The UK Experience

Simon Kennon, Andrew SP Sharp

Watch time: 13m 46s

Articles by Andrew SP Sharp, Professor of Cardiology

Can Interventional Cardiologists Help Deliver the UK Mechanical Thrombectomy Interventional Programme for Patients with Acute Ischaemic Stroke? A Discussion Paper from the British Cardiovascular Interventional Society Stroke Thrombectomy Focus Group

Helen Routledge, Andrew SP Sharp, Jan Kovac, et al

Published:

Citation: Interventional Cardiology 2022;17:e07.

DOI:

https://doi.org/10.15420/icr.2021.35
Use of intravascular ultrasound (IVUS) in ambiguous angiograms

Andrew SP Sharp,

Published:

Citation: RadcliffeCardiology.com, September 2018

DOI:

https://doi.org/10.15420/rc.2018.m015
Fractional Flow Reserve: Does a Cut-off Value add Value?

Shah R Mohdnazri, Thomas R Keeble, Andrew SP Sharp, et al

Citation: Interventional Cardiology Review 2016;11(1):17–26

DOI:

https://doi.org/10.15420/icr.2016:7:2