Pulsed Field Ablation Hub

Watch 2 recorded cases presented at AF Symposium 2026 by Dr Devi Nair, showcasing early clinical experience with Sphere‑360™ catheter.

At AF Symposium 2026, Dr Petr Peichl performed a live AF ablation in a patient undergoing repeat ablation using the Sphere-9™ catheter, showcasing its unique high-density mapping and dual-energy ablation capabilities. 

Watch a series of presentations and panel discussions from AF Symposium 2026 highlighting innovations that enable efficient, rapid lesion creation and streamlined workflows for strong acute and long-term outcomes for atrial fibrillation ablation.

Watch a live redo AF case performed by Dr Miguel Valderrabano highlighting the value of the all-in-one Sphere-9™ catheter.

This recorded case, presented at AF Symposium 2026, showcases the first-in-human usage of the PulseSelect catheter™ with real-time contact assessment.

In this video, Prof Lucas Boersma explores the state of PFA in 2025, highlighting key technological innovations, real-world clinical outcomes and evolving procedural strategies.

Watch Dr Chun, Dr Tzeis and Dr Peichl discuss about what is more important for them once safety assumed, durability or efficiency.

Watch Dr Chun, Dr Tzeis and Dr Peichl discuss about what drives a system apart in the ablation highly competitive landscape. Is it versatility? Workflow integration? Watch the full video to know!

Watch Dr Chun, Dr Tzeis and Dr Peichl discuss about RF role in the PFA landscape and the possibilities of integrating both energies.

Watch Dr Chun, Dr Tzeis and Dr Peichl discuss about the different sedation strategies and what you need to take into account for a safe and efficient workflow.

Watch Dr Chun, Dr Tzeis and Dr Peichl discuss about redo procedures and the relevance of durability data.

Watch Dr Chun, Dr Tzeis and Dr Peichl discuss about what matters more to them in the development of future tools for ablation.

Jakub David (Physician Education Specialist at Medtronic) explains the rationale behind Affera being a closed unipolar system and provides guidance on how to interpret the electrogram information it generates.

Dr Verena Tscholl shares her real-world experience with the Affera system, highlighting its workflow integration, mapping precision and lesion durability.

This case demonstrates a challenging redo procedure performed with the Affera platform.

Dr Metzner presents a pulmonary vein isolation plus additional substrate modification case using the Affera system.

At EHRA 2025, top experts gathered to discuss 'The Next Era in Cardiac Ablation: Elevating Efficiency, Safety and Long-term Outcomes'.

At EHRA 2025, top experts gathered to share their real-world insights on pulsed field ablation technologies during a high-impact session.

Step into a new era of cardiac ablation with the PulseSelect™ and Sphere-360™ single-shot catheters, and the Sphere-9™ catheter for wide area focal PF/RF.​ 

*The Sphere-360 catheter is investigational and not for sale in any geography.

Impact of linear ablation in persistent AF on outcomes using a dual-energy, wide footprint ablation catheter.

Dual-energy (RF/PF), focal Sphere-9™ catheter demonstrates efficacy for linear ablation in persistent AFib.

One-year clinical trial data for the next-generation, investigational, Sphere-360™ single-shot PFA catheter show impressive safety, performance and efficiency results for paroxysmal Afib.

*The Sphere360 catheter is investigational and not for sale in any geography.

EHRA 2025 - Positive safety results of the Affera mapping and ablation system for the treatment of ventricular arrhythmias (VA) show a 6% rate of major complication.

In this video Dr Devi Nair presents the late breaking clinical trial results from APHRS 2024 'First Invasive Remapping to Assess Long-term Durability of Pulmonary Vein Isolation Using a Circular Pulsed Field Ablation Catheter'.

Dr Arash Aryana talks through the clinical insights on using the PulseSelect PFA system for treating paroxysmal and persistent atrial fibrillation. 

Dr Elad Anter presents the SPHERE Per-AF IDE comparing Affera Sphere-9 with Thermocool STSF for treating Persistent AF.

In this video from Rhythm Interventions Online 2024, Dr Erich Kiehl presents 'A Streamlined Single Catheter Workflow With Affera Sphere-9 Catheter'.

AF Symposium 2024 – In this interview, investigator Dr Mohit K Turagam (Icahn School of Medicine at Mount Sinai, US) discusses the findings of a sub-study of the MANIFEST-PF registry.

Dr Yury Malyshev (Mount Sinai Hospital, US) joins us to discuss the findings from three studies focusing on the long-term effects of pulsed-field ablation (PFA) on coronary arteries.

Following the success of Rhythm Interventions Online 2022 (30 November – 2 December 2022), here Course Co-director and operator Dr Devi Nair reviews her Pulsed Field and Radiofrequency Ablation of Atrial Fibrillation Using Novel Focal Lattice Tip Catheter with Zero Fluoroscopy case performed live at the event.

Following the success of Rhythm Interventions Online 2022 (30 November – 2 December 2022), here Course Co-director and operator Prof Julian Chun reviews his Pulsed Field Ablation Using Sedation – The Five 'S' Strategy case performed live at the event.

Principal Investigator, Dr Atul Verma (McGill University Health Centre, CA) joins us on-site at ACC's 2023 Scientific Sessions to outline the findings of the PULSED-AF Trial (Medtronic Cardiac Rhythm and Heart Failure) (NCT04198701).

EHRA 24 - We interview Dr Vivek Reddy (Icahn School of Medicine at Mount Sinai, US) on a first-in-human clinical trial of a novel conformable "single-shot" pulsed field ablation (PFA) catheter for pulmonary vein isolation (PVI).

Dr Vivek Reddy provides an overview of the ADVENT RCT results.

Prof Gerhard Hindricks presents insights on elevating safety and improving procedural workflow in PFA.

Dr Melanie Gunawardene presents Energy Source Selection and Optimising Outcomes for AF Ablation - The Case for PFA.

A discussion of persistent Afib workflows using the Affera™ Mapping and Ablation System.

Join Dr Nicholas Olson as he shares insights on optimizing atrial fibrillation (AFib) ablation using the Sphere-9^TM catheter and Affera^TM mapping and ablation system. 

This webinar will explore an in-depth concomitant case presentation utilizing the PulseSelect™ PFA system and an appendage closure device, executing the procedure with 3D mapping and Intracardiac Echocardiography (ICE).

Learn how FlexCath Cross™ transseptal solution enables the zero-exchange workflow with both PulseSelect™ pulsed field ablation system and Sphere-9™ mapping and ablation catheter supporting a more efficient and seamless clinician and patient experience.

This talk, presented by Dr Jacob Koruth, provides a comprehensive review of the Affera™ Mapping and Ablation System along with the Sphere-9™ Catheter.

Dr Douglas Gibson shares real-world experience using the Affera™ Mapping and Ablation System through the narration of a recorded clinical case.

Dr Tyler Taigen reviews the clinical data and evidence supporting the use of the Affera™ Mapping and Ablation System.

Faculty answer audience questions, offer expert insights and participate in an interactive discussion.

Dr Jay Raval presents a talk on the pathophysiology of hemolysis.

Dr Atul Verma discusses hemolysis with different PFA systems.

Dr Stavros Mountantonakis delivers a presentation on real-world experience with PFA and factors involved in selecting the right patients.

The faculty answer audience questions, offer expert insights and participate in an interactive discussion.

Dr Devi Nair offers a comprehensive overview of lesion durability and workflow with the PulseSelect™ PFA System.

Dr Gaurang Gandhi discusses the implementation of a standardized workflow in a multi-operator center.

The faculty answer audience questions, offer expert insights and participate in an interactive discussion.

Dr Atul Verma gives an overview of PFA, cell death and the sequence of events. 

Dr Atul Verma explains the electroporation zones and how pulse parameters are optimised.

Dr Atul Verma explains monopolar vectoring and bipolar vectoring.

Dr Atul Verma discusses hemolysis, coronary spasm and incidental heating.

Dr Atul Verma explains why contact matters with PFA.

Dr Atul Verma discusses whether PFA is really tissue specific or cell specific.

Dr Devi Nair offers a comprehensive overview of lesion durability and workflow with the PulseSelect™ PFA System.

Dr Gaurang Gandhi discusses the implementation of a standardized workflow in a multi-operator center.

The faculty answer audience questions, offer expert insights and participate in an interactive discussion.

In this video, Dr Atul Verma provides an insightful overview of the safety considerations associated with PFA.

Prof Damijan Miklavcic discusses how electroporation works, where it is used today and more.

Prof Damijan Miklavcic discusses tissue selectivity and what occurs on a cellular level.

Prof David Haines explores on the potential benefits of PFA, PFA ablation characteristics and more.

Dr Atul Verma presents a comprehensive overview of PFA, offering expert insights.

Prof Lucas Boersma gives a brief welcome to the programme and introduces his experience with PulseSelect.

Dr Atul Verma presents the key safety considerations with PulseSelect and shares his own experience.

Dr Atul Verma and Prof Lucas Boersma discuss their insights on PulseSelect PFA.

Dr Stephen Tuohy presents his experience with PulseSelect and shares two detailed video case examples.

Prof Lucas Boersma, Dr Atul Verma and Dr Stephen Tuohy address key questions, providing expert responses and engaging in an interactive discussion.

Case Site: IKEM, Prague, Czech Republic

Case Operator: Josef Kautzner, MD

Case Site: Na Homolce Hospital, Prague, Czech Republic

Case Operators: Vivek Reddy, MD, and Petr Neuzil, MD, PhD

Case Site: Southcoast Health, Fall River, MA

Case Operator: Nitesh Sood, MD

Faculty deliver a series of presentations on the topic of 'Catheter Ablation for Persistent Atrial Fibrillation: Beyond PVI'.

Prof Josef Kautzner presents a case at AF Symposium 2025.

Dr Devi Nair presents a case at AF Symposium 2025.

A live case at AF Symposium 2025 from Lenox Hill Hospital, New York.

Chair: Bradley Knight (Chicago, US)

Case Operator: Usman Siddiqui (Florida Cardiology, Orlando, US)

Panel: Andrea Natale (Austin, US); Nitesh Sood (Boston, US)

Chair: Devi Nair (Jonesboro, US)

Case Operator: Julian Chun and David Schaack (CCB Markus Krankenhaus, Frankfurt, DE)

Panel: Andreas Metzner (Hamburg, DE); Andrea Sarkozy (Brussels, BE)

Chair: Devi Nair (Arkansas, US)

Case Operator: Lucas Boersma (St Antonius Ziekenhuis, Nieuwegein, NL)

Panel: Andreas Metzner (Hamburg, DE); Suneet Mittal (New York, US)

In this PFA Live Case Summit you will see the Affera mapping and ablation system and lattice tip catheter used to treat a persistent AF patient.

In this PFA Live Case Summit a circular array catheter will be used along with 3D mapping to conduct PV isolation.

In this PFA Live Case Summit Prof Josef Kautzner will discuss the use of a focal lattice-tip to treat VT.

In this PFA Live Case Summit Dr Vivek Reddy will discuss the use of a conformable lattice single shot PFA Catheter to treat a PAF patient.

Prof Julian Chun and Dr Boris Schmidt present a live case from Rhythm Interventions Online 2023.

Prof Julian Chun and Dr Boris Schmidt present a live case from Rhythm Interventions Online 2023.