Dr Alexander Lyon MA BM BCh PhD FRCP, is a Senior Lecturer in Cardiology at Imperial College London and a Consultant Cardiologist at the Royal Brompton Hospital.
Areas of interest :
His clinical interests are in the field of heart failure, chemotherapy cardiomyopathy and Takotsubo cardiomyopathy, and he is the theme leader for heart failure research in the NIHR-funded Biomedical Research Unit at the Royal Brompton Hospital.
He is the UK National Coordinating Investigator for the first myocardial gene therapy trial in Europe for chronic heart failure: A Phase 2b, Double-Blind, Placebo-Controlled, Multinational, Multicenter, Randomized Study Evaluating the Safety and Efficacy of Intracoronary Administration of MYDICAR® (AAV1/SERCA2a) in Subjects with Heart Failure: CUPID2 Trial (ClinicalTrials.gov identifier: NCT00534703; EudraCT : 2012-001700-37).
He is the Clinical Lead Investigator for the first myocardial gene therapy trial in patients with left ventricular assist devices: Investigation of the safety and efficacy of AAV1/SERCA2a gene transfer in patients with chronic heart failure and a left ventricular assist device: The SERCA-LVAD trial (ClinicalTrials.gov Identifier: NCT00534703; EudraCT : 2007-002809-48).
Telephone : +44 (0)20 7594 3409
Email : R.Middleton@rbht.nhs.uk