AdaptivCRT™ Algorithm for Chamber and Timing Optimisation in CRT Devices: What Is the Effect in a Real-World Population?

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In this webinar, experts in Cardiac Resynchronisation Therapy (CRT) will show how the AdaptivCRT™ algorithm improves the hemodynamic function of the heart and leads to better patient outcomes. Dr Ulrike Neuhold (Krems, AT) will present the echocardiographic impact of left ventricular only pacing, synchronised with spontaneous right ventricular conduction using AdaptivCRT; Dr Maurizio Lunati (Milan, IT) will show the latest clinical evidence in a real-world population and Prof Carina Blomström-Lundqvist (Uppsala, SE) will moderate the session.

Performed By:

Maurizio Lunati

Maurizio Lunati

Ulrike Neuhold

Ulrike Neuhold

Moderated By:

Carina Blomström-Lundqvist

Carina Blomström-Lundqvist

This webinar is supported by:

Key Learning Objectives

  • The issue of non-response to CRT and how this can be addressed using device algorithms.
  • The benefits of pacing only the left ventricle synchronised with spontaneous right ventricular conduction in CRT patients.
  • The latest clinical results of AdaptivCRT™ in a real-world population.

Target Audience

  • Cardiologists/electrophysiologists and HF specialists involved in the implantation and/or follow-up of cardiac resynchronisation therapy devices.
  • Allied healthcare professionals such as physiologists, hospital technicians or nurses involved in cardiac resynchronisation therapy devices.

Faculty Biographies

Maurizio Lunati

Maurizio Lunati

Dr Maurizio Lunati is Director of Clinical Cardiac Electrophysiology and Cardiac Pacing Unit and Chairman of the Department of Cardiology/Cardiac-Thoracic-Vascular Surgery "A. De Gasperis", Niguarda Hospital, Milan, Italy. 

Dr Lunati is lecturer at Milan-Bicocca University and Varese-Insubria University. He is the past Director of the Cardiac Pacing Course of the Educational Committee of the EHRA (European Heart Rhythm Association), branch of the ESC (European Society of Cardiology).

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Ulrike Neuhold

Ulrike Neuhold

Dr Ulrike Neuhold is working as a Cardiologist in the University Hospital Krems, Austria and in her work, she focuses on electrophysiology, echocardiography, interventional cardiology and the implantation of devices. She is providing echocardiography courses in Austria: echo is an important consideration in the indication for CRT and after CRT implantation, she always checks whether the dyssynchrony has disappeared.

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Carina Blomström-Lundqvist

Carina Blomström-Lundqvist

Dr Carina Blomström-Lundqvist is Professor of Cardiology at the Department of Cardiology, Institution of Medical Science, Uppsala, Sweden.

Dr Blomström-Lundqvist graduated in medicine in 1976, she went on to specialize in cardiology and internal medicine, and started research on haemodynamics and myocardial metabolism in patients with dilated cardiomyopathy. With the developments in electrophysiology she switched her research interest towards arrhythmias and after 3 years she defended her PhD thesis on the diagnostic and prognostic implications of arrhythmogenic right ventricular dysplasia in 1987 in Gothenburg, Sweden.

At Uppsala, Dr Blomström-Lundqvist has become research leader for the arrhythmia unit, mainly focusing on research related to atrial fibrillation (AF). In collaboration with the Department of Thoracic Surgery, procedures for Maze surgery followed by thoracoscopy epicardial atrial fibrillation ablations were initiated.

Dr Blomström-Lundqvist has also served as scientific secretary to the Swedish Society of Medicine and is presently chair of the Heart Rhythm Group of the Swedish Society of Cardiology.

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Key References

1. Birnie D, et al. Continuous optimisation of cardiac resynchronisation therapy reduces atrial fibrillation in heart failure patients: results of the Adaptive Cardiac resynchronisation therapy trial. Heart Rhythm 2017;14:1820-1825.

2. Birnie D, et al. Clinical Outcomes with Synchronised Left-Ventricular Pacing: Analysis of the Adaptive CRT Trial. Heart Rhythm 2013;9(10):1368-1374.

3. Krum H, et al. A novel algorithm for individualised cardiac resynchronisation therapy: rationale and design of the Adaptive CRT trial. Am Heart J 2012;163:747-752.

4. Martin DO, et al. Investigation of a novel algorithm for synchronised left ventricular pacing and ambulatory optimisation of cardiac resynchronisation therapy: results of the Adaptive CRT trial. Heart Rhythm 2012;9(11):1807-1814.

5. Singh JP, et al. Improved Survival with Dynamic Optimisation Of CRT Pacing Using AdaptivCRT Algorithm: Analysis Of Real-world Patient Data. Presented at HRS congress 2018 (Abstract B-AB37-06).

6. Singh JP, et al. Clinical response with adaptive CRT algorithm compared with CRT with echocardiography optimised atrioventricular delay: a retrospective analysis of multicentre trials. Europace 2013;11:1622-8.

7. Starling RC, et al. Impact of Novel Adaptive Optimisation Algorithms on 30-Day Readmissions: Evidence from the Adaptive CRT Trial. JACC Heart Failure 2015;7:565-572.

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