In this Meet the Experts session, from e-SPACE Cardio-Renal-Metabolic 2024, chair Dr Ileana Piña (Thomas Jefferson University, US) is joined by Dr Iris Beldhuis (University Medical Center Groningen, NL) and Prof David Wheeler (University College London, UK) to discuss guideline-directed medical therapy (GDMT) and long-term hyperkalemia management in cardiorenal patients.