Checkmate by Checkpoint: Trials and Tribulations of Novel Immune Checkpoint Inhibitor Associated Myocarditis
Join Dr Dominic Vickers (Prince of Wales Hospital, AU), Dr Daniel Chen (Prince of Wales & St George Hospitals, AU) and Dr Charlotte Lemech (University of New South Wales, AU) as they present a case of fulminant immune checkpoint inhibitor myocarditis administered as part of a Phase 1 clinical trial associated with challenging arrhythmic complications. They will be joined by Prof Dan Lenihan (Saint Francis Healthcare System, US) and Prof Joe Carver (University of Pennsylvania, US) to discuss the role and importance of cardiac surveillance and cardio-oncology collaboration in cancer trials.
The partnership combines Radcliffe’s rapidly growing global community and expertise in delivering the most innovative virtual events, with the knowledge and experience of IC-OS’s members, to curate broadcasts that challenge current practice and have real-world patient benefits.
This broadcast is for cardiologists, haematologists, oncologists, nurse practitioners, nurses and pharmacists.
The International Cardio-Oncology Society is a committed group of professionals throughout the world who are striving to protect the cardiovascular health of all patients who are undergoing cancer therapy. By optimising the cardiac status of patients with cancer before, during and after their treatment, IC-OS is collectively improving the overall outcomes including survival and quality of life. IC-OS aims to provide the latest scientific and clinical education and research for anyone treating patients with cancer in the hopes of enhancing cardiovascular protection.
This is an independent activity run by the International cardio-oncology Society (ICOS) and co-produced in collaboration with Radcliffe Cardiology. IC-OS has been provided support to deliver this webinar series by AstraZeneca, BMS/Pfizer Alliance, Eli Lilly and Roche through an unrestricted educational grant to cover organisational costs and has had no input into the agenda or content of this educational activity. Radcliffe Cardiology has received no industry funding.
This broadcast is supported by
Dr Dominic Vickers is a Cardiology Advanced Trainee at the Prince of Wales Hospital, Sydney, AU.
Dr Vicker's has an interest in advanced cardiac imaging, cardio-oncology and health systems. He is especially interested in developing technologies and how these can be utilised to improve patient outcomes and health efficiencies.
Dr Daniel Chen is a Consultant Cardiologist at the Prince of Wales & St George Hospitals, Sydney, AU. He is also a senior lecturer and researcher through the Hatter Cardiovascular Institute at University College London (UCL).
Dr Chen specialises in cardio-oncology, heart failure and cardiac imaging. His research interests include cardiotoxicities associated with immunotherapies and in breast cancer patients and cancer survivorship.
Dr Charlotte Lemech is a Medical Director and Medical Oncologist at University of New South Wales, Sydney, AU. She works in Scientia Clinical Research (SCR), the first publicly funded purpose-built early phase clinical trials centre in UNSW.
Dr Lemech conducts first-in-human and first-in-patient studies in cancer and across other disciplines, both for novel therapies as well as methods of disease diagnosis and detection. After completing her FRACP in medical oncology in the SESIAHS network, Dr Lemech worked for 4 years in London at an early phase clinical trials unit, Sarah Cannon Research UK, and completed a MD(res) at University College London.
She has experience in managing phase I-III clinical trials across a spectrum of tumour streams and molecular targets including immunotherapy, PI3K/Akt, RAF/MEK, FAK, FGFR and others.
Prof Daniel Lenihan is a cardio-oncologist specialising in cardiology, heart disease and advanced heart failure, at Saint Francis Healthcare System, Cape Girardeau, US.
He is a co-Founder and Board Member of the International Cardio-Oncology Society (ICOS), which is an international professional association whose primary goal is to eliminate cardiac disease as a barrier to effective cancer therapy.
He is actively involved in patient care as the Director of the Cardio-Oncology Programme, Cardiac Rehabilitation, and the Heart Failure clinic at Saint Francis Healthcare System.
Prof Joe Carver is the Bernard Fishman Clinical Professor of Medicine at the Abramson Cancer Center of the University of Pennsylvania, the Chief Operating Officer of the Abramson Family Cancer Research Institute and the Chief of Staff of the Abramson Cancer Center.
He is the Director of the Thalheimer Cardio-oncology Center at the Abramson Cancer Center and his clinical practice is in the subspecialty of cardio-oncology.