Repair or Replace: What Are We Learning From Real-World Studies?

Published: 02 December 2022

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What are real-world studies telling us about selecting between repair or replace strategies for leaky valves? In this series of videos, we bring you up to date with how the dynamic is changing in favour of transcatheter approaches for a great number of patients, and provide some practical guidance for patient selection in both tricuspid and mitral regurgitation. We also explore how a rapidly accumulating body of real-world evidence is starting to shed light on new patient groups that stand to benefit from transcatheter strategies, and seek expert views from both a surgical and interventional perspective on the future success of these treatments.

Filmed following data released at PCR London Valves 2022, our faculty examine some of the latest real-world data on mitral and tricuspid regurgitation and put this data into context for practitioners.

This programme is supported by an educational grant from Abbott.

Learning Objectives

  • Describe the value of real-world data in the treatment of mitral and tricuspid regurgitation
  • Review how patient selection for repair or replacement strategies may change in the near future
  • Identify patient groups in whom transcatheter repair and replacement strategies may be preferable over surgical approaches
  • Understand the value of surgical teams for transcatheter valve interventions
  • Recall the latest real-world evidence on transcatheter repair and replacement treatments for tricuspid and mitral regurgitation

Target Audience

  • Interventional Cardiologists
  • Cardiac Surgeons
  • Heart Failure Specialists
  • General Cardiologists

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Faculty Biographies

Anita W Asgar

Anita W Asgar

Interventional Cardiologist

Dr Anita Asgar is an Interventional Cardiologist working at the Montreal Heart Institute, and Associate Professor of Medicine at the University of Montreal.

Dr Asgar specialises in transcatheter valve interventions, congenital interventions and cardiac MRI. She is the lead cardiologist for the transcatheter mitral/tricuspid valve program at the Montreal Heart Institute. Her research interests include the treatment and management of valvular heart disease and cost-effectiveness analysis and she is currently the Director of Transcatheter Valve Therapy Research at the Montreal Heart Institute.




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Paolo Denti

Paolo Denti

Paolo Denti is responsible for the Functional Department of Transcatheter Therapy of Structural Heart Disease in the Department of Cardiac Surgery at the IRCCS Ospedale San Raffaele in Milan under the supervision of Professor Alessandro Castiglioni. 

After graduating in Medicine and Surgery in 2004 with top marks from the University of Vita-Salute San Raffaele, he completed his specialization in cardiac surgery in 2008 at the same university. 

He is mainly engaged in the treatment of diseases of the aortic, mitral and tricuspid heart valves (insufficiency and stenosis) and coronary surgery. 

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Marta Sitges

Marta Sitges

Director, Cardiovascular Institute

Prof Marta Sitges is a senior consultant non-invasive cardiologist at the Cardiovascular Institute in Hospital Clinic and Professor of Medicine at the University of Barcelona. She has also been the Director of the Cardiovascular Institute since October 2015.

Her main clinical practice is related to clinical and interventional echocardiography, sports cardiology and heart valve disease. She has an extensive publication track in these fields with participation in leading National and International meetings, she has received more than 60 peer reviewed grants and directed multiple MD and PhD thesis. 

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Maurizio Taramasso

Maurizio Taramasso

Specialist in cardiac surgery

Specialist in cardiac surgery since 2014, Dr Maurizio Taramasso has completed his surgical training at the San Raffaele University Hospital in Milan, Italy. He has also done specific cross-training in interventional cardiology and heart valve transcatheter therapies (mitral and aortic) at the San Raffaele University Hospital. His main areas of interest include surgical and catheter treatments of valvular heart disease (transfemoral and transapical TAVI, MitraClip) and heart failure. He is author and co-author of numerous publications on this topic.

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Philipp Lurz

Philipp Lurz

University Medical Center Mainz, Mainz, Germany

Prof Philipp Lurz is Director of the Department of Cardiology Universitätsmedizin Mainz, Germany. Prior to this, he served as Deputy Head of the Department at Heart Center Leipzig, Germany. Previously, Prof Lurz was a Clinical Research Fellow at Great Ormond Street Hospital for Children NHS Foundation Trust. He completed his education at the University of Leipzig, and is a member of the German Society of Cardiology. Philipp is widely published in leading international peer-reviewed journals.

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