Optimising RAASi Management in Cardiorenal Patients: An Expert Roundtable

Published: 23 April 2024

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In this on-demand version of the live roundtable, cardiologists Dr Shelley Zieroth (University of Manitoba, Winnipeg, CA) and Dr Aaron Wong (Princess of Wales Hospital, Wales, UK) join nephrologists Dr Andrew Frankel (Imperial College Healthcare NHS Trust, London, UK), and Dr Manish Sood (University of Ottawa, CA) to discuss the nuanced landscape of RAASi management in cardiorenal patients.


In this discussion, our expert faculty consider approaches to optimal RAASi dosing and strategies to improve patient outcomes. The programme integrates data-driven insights, established guidelines, and expert consensus, offering participants a holistic understanding of RAASi management.


A case study highlights how to overcome barriers to optimal guideline-directed medical therapy and panel discussion will bridge theory and real-world application, providing you with actionable tools to implement optimal practices in your daily clinical pursuits.

This programme is supported by an unrestricted educational grant from AstraZeneca.

Learning Objectives

  • Describe the prevalence and clinical impact of sub-optimal RAASi use in cardiorenal patients
  • Recall key messages from current guidelines, consensus and clinical evidence for optimised RAASi management in cardiorenal patients
  • Describe common barriers to optimise RAASi management strategies
  • Use expert-led guidance to develop a practical approach to overcoming the barriers to RAASi use and the reinitiation/up-titration of therapy

Target Audience

  • Cardiologists
  • Heart Failure Specialists
  • Nephrologists
  • Other Allied HCPs

More from this programme

Part 1

RAASi Management in CKD/HF: What We Should Be Doing

Part 2

RAASi Management in CKD/HF: What Is Happening in The Real World?

Part 3

Key Learnings / Summary

Faculty Biographies

Andrew Frankel

Andrew Frankel

Consultant Nephrologist

Dr Andrew Frankel has been working as a consultant nephrologist at Imperial College Healthcare NHS trust since 1995. He has experience in managing all aspects of kidney disease but has a particular interest in relation to the management of diabetes in the context of kidney disease. Over the years he has maintained a significant research interest in relation to diabetes and kidney, both in terms of how diabetes affects the kidneys leading to deterioration in kidney function, but also in relation to how the presence of kidney disease influences the management of diabetes.  Because of this experience, Dr Frankel has played a significant role in the development of national guidelines on the management of diabetes in the context of kidney disease. He is a regular speaker both locally and nationally and indeed internationally in relation to matters pertaining to diabetes and the kidney.

In collaboration with colleagues within Imperial College and indeed both…

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Shelley Zieroth

Shelley Zieroth

Director, Heart Failure and Heart Transplant Clinics

Dr Shelley Zieroth is Professor at the College of Medicine, Max Rady Faculty of Health Sciences, University of Manitoba, as well as Director of the Heart Failure and Heart Transplant Clinics at St Boniface Hospital in Winnipeg, Canada. She is also Head of the Medical Heart Failure Program for Cardiac Sciences Manitoba.

She is involved in several heart failure clinical trials as a PI, National Lead or Executive Committee member. She is the Past President of the Canadian Heart Failure Society and Co-Chair of the Canadian Cardiovascular Society Heart Failure Guidelines. She is co-chair of Canada’s largest annual heart failure meeting, HF Update, and Past President of the Federation of Medical Women of Canada.

Dr Shelley Zieroth is an Editorial Board member of Cardiac Failure Review.

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Aaron Wong

Aaron Wong

Consultant Cardiologist

Dr Aaron Wong is consultant cardiologist and general physician at the Princess of Wales Hospital, Wales, UK and is also an honorary lecturer at the University of Cardiff, UK.

His research interests include heart failure and cardiometabolic disease.

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Manish Sood

Manish Sood

Assistant Professor of Medicine

Dr Manish Sood is an Assistant Professor of Medicine at the University of Ottawa with cross appointment at the School of Epidemiology and Public Health, Scientist at the Ottawa Hospital Research Institute and the Institute for Clinical Evaluative Sciences, Deputy Editor- in- Chief and founder of the Canadian Journal of Kidney Health and Disease, and holds the Jindal Research Chair for the Prevention of Kidney Disease. 

He completed his undergraduate (BSc) at Carleton and Lancaster University (UK) followed by medical school, internal medicine and nephrology residency training at the University of Toronto. He began his career as a clinical nephrologist at the St Boniface Hospital in Winnipeg, Manitoba, gradually developing an interest in research and clinical epidemiology and in 2013 became a clinician scientist. He completed his Masters in Science in Epidemiology at the University of Ottawa. 

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Lina Eissawi
Important and interesting talk.
Lina Eissawi
Important and interesting talk.