In this short interview from HRS 2022, Dr Andreas Rillig (University Heart and Vascular Center Hamburg, Hamburg, DE) joins us to discuss the outcomes of a sub-analysis of EAST-AFNET4. This multicentre randomised trial compared the strategy of early initiation of rhythm-control therapy with usual care in patients with heart failure.

Discussion points: 
1. Aim of this sub-analysis
2. Patient cohort and study design
3. Main findings
4. Findings in relation to main cohort of EAST-AFNET4
5. Take-home messages for clinicians

Recorded onsite at HRS 2022, San Francisco.