Patients with AF have an increased risk of dementia and clinical stroke. Dr David Conen (Mcmaster University, Hamilton, ON, CA) discusses the results of this large cohort study aimed at investigating if dementia can be mitigated using novel oral anticoagulation (OAC). He also sheds light on what further studies are needed in follow-up to these results.
1. Why did you conduct this study and patient population?
2. What was the study design and endpoints?
3. What were your results?
4. Were there differences between the anticoagulants used?
5. What conclusions can be made as a result of this study and what further research needs to be conducted?