Getting it Right First Time in Severe Aortic Stenosis – Key Insights for Long Term Success

Published: 12 April 2022

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In this symposium, part of Transcatheter Interventions Online 2022, Dr Colum Owens and Prof Mark Spence from Royal Victoria Hospital, Belfast perform a TAVI implantation with a focus on preserving future coronary access. Before the live case, Prof Ole De Backer and Dr Darren Mylotte will present on current trends in TAVI and key considerations for first choice valve in low-risk populations.


Note, this on-demand version is not CME accredited. 

This symposium is supported by an unrestricted educational grant by Boston Scientific.

Key Learning Objectives

  • Recall current and predicted trends in TAVI with respect to preserving coronary access
  • Consider determining factors for choosing valves in low risk populations
  • Discuss solutions for maximising valve durability and haemodynamics and for treating degenerated TAVI

Target Audience

  • Interventional cardiologists
  • Surgeons with an interest in transcatheter treatment strategies for coronary and structural heart disease
  • Interventional cardiology nurses

More from this programme

Part 1

Welcome & Introduction

In the first chapter, Prof Ole De Backer and Dr Darren Mylotte open the symposium by providing a short presentation and discussion on 'Key Considerations in Younger Patients'.

Part 2

Introduction to Live Case from Royal Victoria Hospital, Belfast

In the second chapter, we cut to Belfast where Dr Colum Owens and Prof Mark Spence introduce the commissural alignment case and provide an explanation of the case along with an overview of the patient.

Part 3

How to Obtain Commissural Alignment

In chapter three, we are back with Prof Ole De Backer and Dr Darren Mylotte in the studio, where they provide a short presentation about how to obtain commissural alignment with the ACURATE neo2.

Part 4

Commissural Alignment: Live Case

For the final chapter, we stay with Dr Colum Owens and Prof Mark Spence in Belfast where they perform a commissural alignment live procedure. The symposium is concluded with a few questions asked by the live audience and closing remarks from Prof De Backer.

Faculty Biographies

Ole De Backer

Ole De Backer

Interventional Cardiologist

Prof Ole De Backer is an internationally renowned interventional cardiologist working at Rigshospitalet, Copenhagen University Hospital, Denmark and is an expert in structural heart interventions – among others transcatheter heart valve interventions, percutaneous left atrial appendage closure and thoracic endovascular aortic repair. Special areas of interest are the development and adoption of a fully percutaneous, minimal invasive approach for different structural heart interventions and the use of advanced cardiac imaging tools for planning and guidance of these interventions. He is actively involved and leading several research projects in the field of transcatheter heart valves and percutaneous left atrial appendage closure. 

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Darren Mylotte

Darren Mylotte

Consultant Cardiologist

Dr Darren Mylotte graduated from RCSI Medical School in 2001, obtained membership of the Royal College of Physicians in Ireland in 2004, and completed the Irish Cardiology Specialist Training Scheme. He and was conferred with a Doctor of Medicine (MD) thesis in 2010 by the Royal College of Surgeons in Ireland and has also undertaken a PhD thesis. N the subject of Transcatheter Aortic Valve Implantation (TAVI) at the world renowned ThoraxCentre in Rotterdam, The Netherlands.


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Colum Owens

Colum Owens

Consultant Cardiologist

Dr Colum Owens, MBBCH is a Consultant Cardiologist at Belfast Health & Social Care Trust. His research interests are Cardiology, Transcatheter Valve Intervention, Patent Foramen Ovale, Left Atrial Appendage Occlusion, Congenital Heart Disease.

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Mark Spence

Mark Spence

Prof Mark Spence graduated with honours in Medicine from Queens University Belfast in 1995 and progress to Membership of the Royal College of Physicians (Edinburgh) in 1998. 

He trained in cardiology in Belfast and then completed subspecialty training in congenital heart disease as a fellow in the inaugural Adult Congenital Heart Disease programme at Guys & St Thomas’ and the Royal Brompton Hospital, London.

His MD thesis was awarded by Queens University Belfast in 2002. He then completed a fellowship in interventional cardiology at The Royal Jubilee Hospital, British Columbia, Canada before taking up a consultant cardiology post in 2007 at the Royal Victoria Hospital, Belfast Trust. He joined Mater Private Network in November 2021.

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