Contemporary Techniques for TAVI in Complex Patients

Published: 24 March 2023

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    Didier Tchétché, Kendra J Grubb, Ignacio J Amat-Santos, Darren Mylotte
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    Didier Tchétché, Kendra J Grubb, Ignacio J Amat-Santos, Darren Mylotte
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This symposium, part of Transcatheter Interventions Online 2023, and chaired by Dr Didier Tchétché (Clinique Pasteur, Toulouse, FR), presented and discussed the importance of first valve selection. The faculty considered why the choice of the first valve matters in younger and lower-risk patients with longer life expectancy. They also showed how the technical refinements in implementation are going to play a positive role and presented a 'how-to' guide on how to select and treat bicuspid patients for positive clinical outcomes.

This programme is supported by an unrestricted educational grant by Medtronic.

Learning Objectives

  • Recall why valve choice matters for younger patients
  • Review recent TAVI clinical data showing durability in younger patients
  • Share experiences of incorporating the Cusp Overlap Technique into your practice
  • Discuss how to optimise TAVI placement in bicuspid patients

Target Audience

  • Interventional Cardiologists
  • Surgeons with an interest in transcatheter treatment strategies for coronary and structural heart disease
  • Interventional Cardiology Nurses

More from this programme

Part 1

Welcome & Introduction

Dr Didier Tchétché introduces the symposium agenda and panel.

Part 2

Considerations for First Valve Implantation

Dr Kendra Grubb presents considerations for the first valve implantation by introducing a patient case study and by discussing data released in recent trials.

Part 3

Valve Placement: Right Place, Every Time!

Dr Amat-Santos dives into the technical aspects of the TAVI procedures. He will examine how TAVI implantation has been improved in recent years, by looking at two specific techniques, cusp overlap technique and commissural alignment.

Part 4

Managing Bicuspid Patients and Optimising Outcomes

Dr Mylotte presents on how to optimise outcomes of TAVI in aortic bicuspid patients. He looks at the challenges and strategies adapted for bicuspid patients.

Part 5


Dr Tchétché closes the symposium by summarising the main points discussed with the panel.

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Faculty Biographies

Didier Tchétché

Didier Tchétché

Didier Tchétché, (Clinique Pasteur, Toulouse, France) Graduated from the University of Paris V where Dr Tchétché obtained his post-graduate diploma of cardiovascular pathology in 2004. From 2004 to 2005, he completed a 12-month fellowship period in the Hemodynamic and Interventional Cardiology department of Clinique Pasteur in Toulouse and from 2005 to 2007 he was Head Assistant at the intensive care unit of Bichât Hospital in Paris.

In 2008, he joined the interventional cardiovascular group in Clinique Pasteur, Toulouse, and he is currently Head of the Structural programme with an experience of more than 5000 TAVI procedures. His main areas of interest are coronary interventions and valvular heart disease. He has been actively involved in many clinical trials involving new technologies and devices in the field of interventional cardiology.

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Kendra J Grubb

Kendra J Grubb

Surgical Director

Dr Kendra Grubb is the surgical director of the Emory Structural Heart and Valve Center. She is also an associate professor of surgery at Emory University School of Medicine.

Kendra is a champion for women's heart disease and is dedicated to improving the lives of all patients through innovation, collaboration and a patient-centred approach to the treatment of cardiovascular disease.

Her clinical interests include valve repair or replacement, coronary artery bypass graft surgery (CABG), transcatheter aortic valve replacement (TAVR) and hybrid coronary revascularization.

Dr Grubb research interests are innovative cardiac surgery technologies. She has led and participated in multiple clinical trials of innovative cardiac surgery technologies, including studies of transcatheter aortic valve replacement (TAVR), MitraClip percutaneous therapy and the GORE® conformable TAG® thoracic endoprosthesis for the primary treatment of…

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Ignacio J Amat-Santos

Ignacio J Amat-Santos

Director, Cardiac Catheterization & Interventional Cardiology

Dr Ignacio J Amat Santos is an interventional cardiologist based in Spain. He is currently the director of cardiac catheterization and interventional cardiology at Hospital Clínico Valladolid.

Dr Amat Santos is the director of cardiac catheterization and interventional cardiology at Hospital Clínico Valladolid. He has clinical and research experience in the percutaneous treatment of coronary and structural heart disease. He is also experienced in clinical cardiology, functional tests and echocardiography.

Dr Amat Santos applied V-WAVE, a device to treat heart failure, for the first time in Europe in his hospital. His scientific activity has given rise to the publication of more than 40 articles and more than a hundred communications in national and international congresses.

Dr Ignacio J Amat-Santos is on the European Cardiology Review Editorial Board.


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Darren Mylotte

Darren Mylotte

Consultant Cardiologist

Dr Darren Mylotte graduated from RCSI Medical School in 2001, obtained membership of the Royal College of Physicians in Ireland in 2004, and completed the Irish Cardiology Specialist Training Scheme. He and was conferred with a Doctor of Medicine (MD) thesis in 2010 by the Royal College of Surgeons in Ireland and has also undertaken a PhD thesis. N the subject of Transcatheter Aortic Valve Implantation (TAVI) at the world renowned ThoraxCentre in Rotterdam, The Netherlands.


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Mohammed Algradi