Chronic total occlusions continue to be one of the most challenging PCI subsets faced by interventional cardiologists. However, with proper training, modern techniques and progressively improving tools, success rates of 90% and above are quite achievable. Furthermore, CTO operators acquire a number of advanced skill sets which enable them to manage non-CTO PCI challenges more effectively across a broad spectrum of complex clinical and anatomical presentations. With this in mind, and with the growing global interest in CTO PCI, we are delighted to bring you ML CTO to the Middle East for the first time.