Developments in Cardiovascular Medicine and Surgery

Login or register to view PDF.
Citation
US Cardiology, 2007;4(2):12-3

Pages

Innovative technologies and refinements of existing therapies are shaping 21st century cardiovascular diagnosis and treatment. Researchers are gaining new perspectives on diseases and their treatment at the cellular and subcellular levels. Cardiologists are evaluating and treating coronary arteries by means of intravascular intervention. Surgeons are shortening recovery times and increasing cost-effectiveness by using minimally invasive techniques. Moreover, innovators are combining treatments in new ways and offering hybrid procedures that confer numerous patient benefits. A few of the most recent developments in the cardiovascular field are reviewed below.

Cardiovascular Medicine

Though still in their early stages, several emerging therapies offer exceptional promise for revolutionizing the practice of cardiovascular medicine. For example, stem cell and genetic techniques are beginning to allow treatment at the cellular and subcellular levels. In addition, non-invasive yet highly sensitive imaging techniques are emerging as alternatives to traditional diagnostic imaging. Cardiovascular care will continue to build on these advances for many years to come.

Stem Cell Treatment

In this technique, stem cells are injected into the heart with the expectation that they will evolve into cardiac cells and replace the damaged cells. This approach has enormous potential to help the heart heal itself, particularly when other treatment options are unavailable. Stem cell therapy continues to expand as short-term follow-up studies reveal blood vessel development, cellular regeneration, and improved perfusion in treated areas. Currently, clinical investigators are focusing on four conditions: acute myocardial infarction (MI), myocardial ischemia without revascularization, ischemic cardiomyopathy, and peripheral vascular disease. Researchers are considering the relative efficacies of different cell types and delivery methods for treating these conditions.

Pages

References
  1. Capoccia BJ, Wirthlin L, Shepherd R, et al., Bone marrow-derived aldehyde dehydrogenase expressing cells possess endothelial progenitor function in addition to hematopoietic repopulating ability and aid in blood flow recovery after acute ischemic injury, Blood, 2005;106:Abstract 2663.
  2. Darwin J, Med center spawns new gene team, Houston Business J, 2001. Available at: http://www.bizjournals.com/houston/stories/ 2001/12/10/story5.html
  3. Savino G, Herzog C, Costello P, Schoepf UJ, 64-slice cardiovascular CT in the emergency department: concepts and first experiences, Radiol Med (Torino), 2006;111:481–96.
    Crossref | PubMed
  4. Mack MJ, Aronoff RJ, Acuff TE, et al., Present role of thoracoscopy in the diagnosis and treatment of diseases of the chest, Ann Thorac Surg, 1992;54:403–9.
    Crossref | PubMed
  5. Folliguet T, Vanhuyse F, Constantino X, et al., Mitral valve repair robotic versus sternotomy, Eur J Cardiothorac Surg, 2006;29: 362–6.
    Crossref | PubMed
  6. Mack MJ, Minimally invasive cardiac surgery, Surg Endosc, 2006; 20(Suppl. 2):S488–92.
    Crossref | PubMed
  7. Dooner J, Lee S, Griswold W, Kuechler P, Laparoscopic aortic reconstruction: early experience, Am J Surg, 2006;191:691–5.
    Crossref | PubMed
  8. Brinster DR, Byrne M, Rogers CD, et al., Effectiveness of same day percutaneous coronary intervention followed by minimally invasive aortic valve replacement for aortic stenosis and moderate coronary disease (‘hybrid approach’), Am J Cardiol, 2006;98: 1501–3.
    Crossref | PubMed