TCT 2023 Late-Breaking Science Collection

Published: 09 January 2024

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Overview

Stay up-to-date with our regular review series, View from the Thoraxcenter hosted by Prof Nicolas Van Mieghem and Dr Joost Daemen (Thoraxcenter, Erasmus MC, Rotterdam, NL). In this #TCT2023 edition they provide a short analysis of the most pertinent data from the late-breaking science presentations. 

Short, accessible Expert Interviews were conducted with investigators focusing on study design, key results and applicability of the latest data. 

About the episode

TCT 23 - We are joined by Dr Giovanni Luigi Di Maria (John Radcliffe Hospital, UK) to discuss the findings of the PICSO-AMI-I study (NCT04958421), sponsored by Miracor Medical.

The PICSO-AMI-I study aimed to assess the safety and feasibility of pressure-controlled intermittent coronary sinus occlusion (PiCSO) in patients with ST-elevation myocardial infarction (MI), presenting with TIMI 0 or 1 undergoing percutaneous coronary intervention (PCI) as compared to standard PCI. 25 participants were enrolled in the study, and were randomized 2:1 to either PiCSO or control. 

Results showed that in this patient group, PiCSO assisted pPCI was feasible, though it was associated with a prolonged procedural time and increased contrast dye volume and radiation exposure. PiCSO was not associated with an increased rate of adverse events (device and non-device related) at 6 months follow-up. 

Interview Questions: 

  1. What are the unmet needs of acute myocardial infarction patients?
  2. What is the PiCSO Impulse System, and what are its unique features?
  3. What was the study design and patient population
  4. What were the late-breaking findings?
  5. What further study is needed?

 

Recorded remotely from Oxford, 2023.

 

Editor: Jordan Rance
Video Specialist: Dan Brent

Faculty Biographies

Giovanni Luigi Di Maria

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