Malaysia in Focus: Reverse Cardiac Remodelling

Published: 11 March 2021

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Full programme

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Part 4

of 7

Prevalence of HFpEF on the Rise – Treat HFpEF as a Whole, Not Just the Comorbidities

Andrew JS Coats, David Chew


This reverse cardiac remodelling IME programme brings together a leading faculty of internationally-recognised experts, combining presentations and peer-to-peer discussions to provide comprehensive overview of the latest data and opinion around cardiac remodelling.

Beyond the global focus, this programme also seeks – through insight from Dato' Dr David Chew – to frame and contextualise the topics discussed with specific focus on Malaysia, to help support the education of local physicians on pertinent topics including guideline adherence, emerging data, and best practice.


A CPD-accredited version of this programme is available on Radcliffe Education. Click here for further details.

This independent medical education programme is supported by an unrestricted educational grant from Novartis. The programme has been endorsed by the National Heart Association of Malaysia (NHAM).

Learning Objectives

  • Define cardiac remodelling, with particular focus on the influence of cardiovascular damage, pathogenic risk factors and the structural and functional changes in the left ventricle.
  • List the main clinical implications of cardiac remodelling.
  • Summarise the relationship between circulating biomarkers, such as NT-proBNP, troponin and sST2, with the extent left ventricular remodelling in subjects with HF.
  • Interpret the most recent clinical data from pharmacological and device-based studies in HFrEF and HfpEF.
  • Recall the evidence for reverse cardiac remodelling brought about through ARNi therapy, including (but not limited to) PROVE-HF and EVALUATE-HF.
  • Review real-world insight into the impact that ARNi therapy has on cardiac reverse remodelling.


  • Practicing cardiologists
  • Heart failure specialists
  • Health care professionals involved in the diagnosis and management of patients with heart failure

More from this programme

Faculty biographies