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Part 1 | Session 1 The Science of Ultrasound Renal Denervation: Introduction
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Part 1 | Session 2 Ultrasound Technology – Its Development and Unique Characteristics: Andy Wu
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Part 1 | Session 3 Ultrasound Renal Denervation Preclinical Evidence: Dr Michael Joner
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Part 1 | Session 4 RDN Procedure with Ultrasound Technology: Prof Felix Mahfoud
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Part 1 | Session 5 Panel Discussion: All
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Part 2 | Session 1 The Paradise uRDN System: Dr Andrew Sharp
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Part 2 | Session 3 How to build uRDN centre / therapy pathway: Prof Roland Schmieder
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Part 3 | Session 2 "Ultrasound RDN - Reviewing the Latest Clinical Results" : Joost Daemen
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Part 3 | Session 3 "How to build Interventional HTN Therapy/Practice": Joachim Weil
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Part 4 | Session 1 RADIANCE II Pivotal Trial
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Part 5 | Session 3 ACC 2021 – RADIANCE-HTN TRIO Trial Results with Ajay Kirtane
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Part 5 | Session 4 EuroPCR 2020 – Crossover Results From the RADIANCE-HTN SOLO Trial
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Part 7 | Session 1 ACC 2022 Symposium
Ultrasound Renal Denervation (uRDN) is an innovative therapy option for the treatment of uncontrolled hypertension. uRDN therapy is delivered in a minimally invasive procedure that may lower high blood pressure by treating overactive renal nerves with ultrasound energy.
This page provides an overview of uRDN technology and the latest evidence from its associated RADIANCE clinical program.
The PARADISETM System is Limited to Investigational Use Only in the United States. Approved for distribution in CE mark countries only.

What you will learn:
- How uRDN works and its potential benefits for patients suffering from uncontrolled hypertension
- The clinical evidence supporting uRDN and its implications for the field of hypertension
- The process for building a uRDN centre and therapy network
This page is designed for:
- Interventional cardiologists
- General cardiologists
- Hypertension specialists
- Nephrologists
- Interventional radiologists
More from this programme
Part 2
The Evidence for uRDN
Part 3
From Proof to Practice – Treating Hypertension With uRDN
Part 4
RADIANCE II Pivotal Trial for Paradise Ultrasound Renal Denervation System in Patients With Hypertension
Part 6
Patient Perspective & Provider Referral Development
Faculty Biographies

Chandan Devireddy
Interventional Cardiologist and Associate Professor
Dr Devireddy is an Associate Professor of medicine of Interventional Cardiology at Emory University. He received his medical degree from the University of Michigan in 1998 and completed Internal Medicine training at Duke University in 2001. In 2005, he completed fellowship training in both Cardiovascular Medicine and Interventional Cardiology at Emory University.
His focused expertise is on transcatheter structural heart solutions, minimally invasive techniques to lower blood pressure, and catheter based treatment of complex coronary, heart and vascular disease.

Ajay J Kirtane
Professor of Clinical Medicine
Ajay J Kirtane, is Professor of Medicine at the Columbia University Medical Center (CUMC) and Director of the Cardiac Catheterization Laboratories at NewYork-Presbyterian (NYP) Hospital / CUMC. Dr. Kirtane is an internationally-renowned leader in Interventional Cardiology, specializing in the care of patients with complex coronary and peripheral vascular disease.
In addition to his clinical commitments, Ajay has a strong interest in clinical education and research, serving as Chief Academic Officer of Columbia Interventional Cardiovascular Care. He is a director of the Cardiovascular Research Foundation’s Transcatheter Cardiovascular Therapeutics conference, has served as a director of several international, national, and regional educational conferences, and has participated on the program committees for the scientific sessions of both the American College of Cardiology and American Heart Association. Ajay’s research…

Felix Mahfoud
Professor of Cardiology and Chairman of the Department of Cardiology
Prof Felix Mahfoud is a Professor of Cardiology at the University of Basel and the Chairman of the Department of Cardiology at University Hospital Basel, Switzerland. He also holds a position as Visiting Professor at Harvard-MIT, Biomedical Engineering in Boston, MA.
Prof Mahfoud is board-certified in internal medicine, cardiology, intensive care medicine, emergency medicine and hypertension. He is Deputy Editor of the European Journal of Heart Failure and is a Councillor on the Board of the European Society of Cardiology (ESC) for 2024-2026. Additionally, he chairs both the ESC Communication Committee and the Scientific Documents Committee of the EAPCI for the 2024-2026 term.
He has published more than 500 publications in peer-reviewed journals and contributed as a wiring committee member to the 2019 ESC Guidelines for the…

Naomi Fisher
Associate Professor
Dr Fisher is an endocrinologist at the Brigham and Women’s Hospital, and Associate Professor of Medicine at Harvard Medical School.
She has completed over two decades of clinical research at Harvard University, focusing on cardiovascular endocrinology.
She received her Bachelor of Arts degree in the History and Philosophy of Science from Princeton University, and her medical degree from the University of Pennsylvania.