EuroPCR 2022: Late-breaking Science Video Collection
Published: 13 May 2022
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Views:
2458 -
Likes:
7
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Up Next
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4m 49s
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3m 53sPart 2 | Session 7 EuroPCR 22: Short-Term Clinical Outcomes of ACURATE neo2™
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4m 20s
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2m 18sPart 2 | Session 9 EuroPCR 22: SYNERGY™ Non-inferior to BioMatrix NeoFlex in OCT SORT-OUT VIII
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5m 9s
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7m 18sPart 2 | Session 11 EuroPCR 22: Balloon Vs Self-Expanding Valves in Valve-in-Valve TAVI
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5m 52sPart 2 | Session 12 EuroPCR 22: MitraClip in Atrial Functional Mitral Regurgitation
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2m 15sPart 2 | Session 13 EuroPCR 22: SCB with Micro-Reservoir Technology in Coronary Lesions
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4m 46sPart 2 | Session 14 EuroPCR 22: FORWARD PRO Study Shows No Durability Issues After 3 Years
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4m 25sPart 2 | Session 15 EuroPCR 22: DEB & DES in the Treatment of Diffuse CAD
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3m 16sPart 2 | Session 16 EuroPCR 22: EASTBOURNE Registry indicates Satefy of Sirolimus-Coated Balloon
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4m 27sPart 2 | Session 17 EuroPCR 22: JenaValve TAVR System for the Treatment of Aortic Regurgitation
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7m 7sPart 2 | Session 18 EuroPCR 22: Transcatheter Tricuspid Valve Repair with PASCAL System
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6m 53s
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20m 24sPart 1 | Session 1 EuroPCR 22 Late-breaking Science Preview Joost Daemen, Nicolas M Van Mieghem
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27m 14sPart 1 | Session 2 EuroPCR 22 Late-breaking Science Wrap-Up Nicolas M Van Mieghem, Joost Daemen
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3m 28sPart 2 | Session 1 EuroPCR 22: AQVA Study Shows Superiority in QFR-Based Virtual PCI Arm Simone Biscaglia
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5m 10sPart 2 | Session 2 EuroPCR 22: Patient-Level Pooled Analysis of Ultrasound RDN in radiance-HTN SOLO & Trio Ajay J Kirtane
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7m 50sPart 2 | Session 3 EuroPCR 22: Optimize PRO Interim Analysis Finds New Technique is "Best-in-Class" Kendra J Grubb
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5m 56sPart 2 | Session 4 EuroPCR 22: MASTER-DAPT Sub-Analysis Shows Consistent Results in Complex PCI Patients Marco Valgimigli
Overview
Our regular review series View from the Thoraxcenter hosted by Prof Nicolas Van Mieghem and Dr Joost Daemen (Thoraxcentre, Erasmus MC, Rotterdam, NL) provide a concise analysis of the late-breaking science trials and spotlight questions that could change treatment strategies in interventional cardiology.
Short, accessible Expert Interviews will be available with select faculty focusing on the results, applicability, and impact on future research.
More from this programme
Part 1
View from the Thoraxcenter
Part 2
Expert Interviews
Faculty Biographies
David Leistner
Managing Senior Physician
Prof Leistner is a Managing Senior Physician at the Clinic for Cardiology and Angiology, Charité Berlin, Campus Benjamin Franklin.
Transcript
Aim of This Study
So, the aim of the study was to assess the performance of the ultra thin strut Supraflux Cruz Stent in a large broad cohort of all-comer patients with a certain number, of about one third, high bleeding risk HBR patients.
The Supraflux Cruz Stent
So we investigated the Supraflux Cruz drug-eluting stent, which is a ultra thin strut stent, drug-eluting stent, with strut thickness of about 60 micrometres, independent of the size of the stent, and it has a bioresorbable polymer which allows very fast healing of this stent device.
Key Results
So what we see, that in this all-comer population we see a favourable clinical outcome after PCI using the novel ultra thin Supraflux-Cruz drug-eluting stent. This was non-inferior to the TALENT study, the randomised study, which leads to the use of the Supraflux drug-eluting stent in clinical practice, and for the HBR subgroup of patients within the study, we could show that the Supraflux-Cruz stent was non-inferior for the outcome with the endpoint Doche device orientated clinical outcome in HBR patients.
Take-Home Messages for Practicing Clinicians
So what we see now is where that we have device specific evidence for the use in the broad spectrum of all-comer patients for non-HBR, as well as for HBR patients, to use this novel generation of ultra thin Supraflux-Cruz drug-eluting stent, And for my personal opinion, this is important for every new device to investigate such a device in the highest risk patients we treat every day in the cath lab, and these are HBR patients.
Further Study Needed and Next Steps
As we see in CRUZ-HBR now, the cruz stent seems to be a perfect solution for patient with high bleeding risk and very complex lesions. So the next step would be that on the one hand, you have to challenge this stent in only special situations, For example, CTOs, bifurcations, where this dedicated novel stent can optimise the results, and on the other hand I think this stent opens the possibility to think again about, and minimising the dual antiplatelet therapy, maybe if you use such ultra thin strut stent, it could be enough to treat it after a very clear implantation procedure to treat the patients only with one anti-thrombotic medication, but I think for this unique randomised prospective clinical trials, and I think they are actually in the face of plane.