Translating Evidence, Innovations & Value for Patients with Dr Mandrola

EP 101: Translating Evidence, Innovations & Value for Patients with Dr John Mandrola

Average (ratings)

No ratings

•

Your rating

In this week's episode of Parallax, Dr Ankur Kalra welcomes Dr John Mandrola, a cardiac electrophysiologist practicing in Louisville and the host of the popular podcast "This Week in Cardiology" and author of Sensible Medicine, among other forums.

In this insightful episode, we delve into Dr Mandrola's career journey. He discusses how the beginnings of his career during a period of significant innovations and the reversal of expert opinions profoundly influenced his perspective on medicine, leading to a more conservative stance. Dr Kalra then invites Dr Mandrola to share the motivations that drive his work as a medical journalist and communicator, along with his methods of selecting studies to highlight in his writings and show.

Dr Mandrola emphasizes the importance of bedside medicine and the critical role of translating and interpreting evidence in modern healthcare. Together, Dr Kalra and Dr Mandrola explore the complexities of practicing medicine today and ponder the value propositions associated with the latest innovations.

Dr Mandrola sheds light on what he considers the most promising new advances in the field. He concludes the episode by offering valuable advice to our listeners, advocating for the implementation of innovations grounded in medical evidence and supported by sound policies.

Questions and comments can be sent to “podcast@radcliffe-group.com” and may be answered by Ankur in the next episode.
Guest: @drjohnm Host: @AnkurKalraMD and produced by: @RadcliffeCARDIO.

Read MoreRead Less

Episodes

Up Next

EP 102: Nobility in Small Things with Cardiac Surgeon, Dr Craig R Smith

EP102 • Oct 16, 2023 • 50m 11s

In this inspiring episode, Dr Smith delves into the story behind his book and the motivating circumstances that led him to become an author. Dr Kalra asks Dr Smith about his experience as a leader during the pandemic as a surgeon. Dr Smith shares the story of his unconventional journey into medicine, emphasizing how hard physical labor built his resilience and prepared him for his residency. Dr Kalra also asks about Dr Smith's experience as a surgeon for President Bill Clinton in 2004.

All Episodes

Ep 154: Climate Change and CV Health: From Heat Waves to Heart Risk

Ep 154: Climate Change and Cardiovascular Health: From Heat Waves to Heart Risk

EP154 • Mar 02, 2026 • 29m 37s

In this episode of Parallax, Dr Ankur Kalra speaks with Dr Sameed Khatana, Assistant Professor of Medicine at the University of Pennsylvania and clinical cardiologist at the Philadelphia VA Medical Center. Their conversation examines the growing connection between environmental factors and cardiovascular health.

Ep 153: The 60-Minute Window: Solutions for Faster STEMI Diagnosis

Ep 153: The 60-Minute Window: Engineering Solutions for Faster STEMI Diagnosis

EP153 • Feb 17, 2026 • 36m 31s

In this episode of Parallax, Dr Ankur Kalra welcomes Dr Rakesh Shah, a former interventional cardiologist, Oxford MBA graduate, and founder of DRS.LINQ.

Ep 152: From Risk Factor to Treatment Target: The New Era of Cardiometabolic Medicine

EP152 • Feb 02, 2026 • 38m 33s

In this key episode of Parallax, Dr Ankur Kalra sits down with Prof Naveed Sattar to explore how recent therapeutic breakthroughs are fundamentally reshaping the cardiologist's approach to diabetes management.

Ep 151: Cardiology's 2025 Year in Review with Dr Sukh Nijjer

EP151 • Jan 16, 2026 • 1h 40m 44s

In this highly anticipated annual year-end episode of Parallax, Dr Ankur Kalra welcomes back Dr Sukh Nijjer, an interventional cardiologist in London, for their seventh consecutive year reviewing cardiology's most significant developments.

Ep 150: Building a Legacy in Cardiology: From the NIH to JAMA Cardiology with Robert Bonow

EP150 • Jan 05, 2026 • 50m 44s

In this landmark 150th episode of Parallax marking the start of Season 8, Dr Ankur Kalra welcomes Professor Robert Bonow, Professor of Medicine and Cardiology at Northwestern University and Editor-in-Chief of JAMA Cardiology. This milestone conversation explores the career of one of cardiology's most influential academic leaders and examines how strategic vision, mentorship, and institutional leadership have shaped modern cardiovascular medicine.

Ep 149: The Placebo-Controlled Revolution: Redefining Evidence in Device Trials

EP149 • Dec 19, 2025 • 33m 7s

In this week's episode of Parallax, Dr Ankur Kalra welcomes Prof Rasha Al-Lamee, interventional cardiology consultant and professor of medicine/cardiology at Imperial College London, and deputy editor of JACC. Prof Al-Lamee has transformed interventional cardiology through her pioneering work on the ORBITA trial series and coronary sinus reducer device studies, introducing the paradigm-shifting concept of sham-controlled device trials to the field.

Ep 148: Breaking Down Healthcare Borders: Five Pillars to Revolutionary Access

EP148 • Dec 08, 2025 • 32m 30s

In this episode of Parallax, Dr Ankur Kalra welcomes Dr Sarah Matt, Associate Clinical Professor at Upstate Medical University, health tech strategist, and author of the newly released The Borderless Healthcare Revolution.

Ep 147: From Landfill to Life-Saving: GOMED's Mission to Reimagine Medical Device Distribution

EP147 • Nov 24, 2025 • 38m 44s

In this week's episode of Parallax, Dr Ankur Kalra welcomes Dr Courtney Maxey-Jones, Director of the Coronary Care Unit at Upstate University Hospital and a cardiac anesthesiologist intensivist by training. Dr Maxey-Jones co-founded and serves as Chief Operations Officer of GOMED, a not-for-profit organization transforming how we think about medical device waste and global healthcare equity.

Ep 146: The Heart Function Revolution: Why Prevention Matters at Every Stage of Disease

EP146 • Nov 10, 2025 • 37m 49s

In the latest episode of Parallax, Dr Ankur Kalra welcomes Dr Martha Gulati and Dr Anu Lala for a groundbreaking conversation about reimagining heart failure prevention across the entire disease spectrum.

Ep 145: From NAFLD to MASLD: Unveiling the Cardiovascular Impact of Metabolic Liver Disease

EP145 • Oct 24, 2025 • 30m 36s

In this essential episode of Parallax, Dr Ankur Kalra welcomes Dr Monica Tincopa for a crucial conversation about Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and its profound implications for cardiovascular care.