Post-PCI assessment of coronary physiology

Post-PCI assessment of coronary physiology

Video On Demand

Moderated By
Dr. Nicolas van Mieghem
Erasmus Medical Centre, Rotterdam (NL)
Presented By
Dr. Joost Daemen
Erasmus Medical Centre, Rotterdam (NL)

Dr. van Mieghem will present and moderate this webinar on post-percutaneous coronary intervention (PCI) physiology assessment.

The webinar is intended to educate the viewers on the concept of assessing the (intra-) coronary physiology after a lesion has been treated with an eligible stent device. Dr. van Mieghem will review the existing clinical evidence of this treatment strategy and also present the findings from the FFR SEARCH registry which was done in the Erasmus Medical Center (EMC) Rotterdam (the data was first presented at PCR 2017).

This webinar aims to critically discuss if Post-PCI fractional flow reserve (FFR) could potentially improve outcomes.

A clinical case will be presented which will highlight the procedural aspects of the physiologic assessment pre-PCI, intra-PCI and post-PCI assessment and intravascular imaging (IVUS).


Primary Objectives:
Present the findings from the FFR SEARCH registry and introduce the follow-up trial: FFR REACT
  • Findings FFR SEARCH
  • Discuss imaging results to answer the question, 'what causes results?'
  • Identify and discuss the benefits of using a microcatheter

Introduce the microcatheter-based FFR solution (ACIST RXi®)and high definition intravascular ultrasound (ACIST HDi®)from ACIST Medical Systems

  • Understand more about post-PCI physiology
  • To learn about microcatheter-based post-stent FFR procedures
  • To learn about post-PCI intravascular imaging in high-definition
  • To learn about the clinical evidence of Post-PCI FFR
  • Interventional Cardiologists
  • Assistant Cathlab personnel (Nurses, Technicians, Radiographers)

Dr. van Mieghem joined the department of interventional cardiology in the Thoraxcenter, Erasmus MC in 2010 and is currently Medical Director of the Interventional Cardiology Department. His research focuses on transcatheter heart valve interventions and therapies. A fellow of the European Society of Cardiology (FESC) and an established researcher and author, he has published and co-authored over 100 scientific papers.


Dr. Joost Daemen obtained his degree in Medicine in 2005 in Erasmus University in Rotterdam, his PhD in 2008 and is now an interventional cardiologist at the Thoraxcenter, Erasmus MC, in Rotterdam. His research in the field of interventional cardiology focuses mainly around long-term follow up, safety and efficacy of drug-eluting stents and stent thrombosis where he is involved in a number or trials as Principal Investigator.

  • Briguori C, Nishida T, Adamian M, et al. Assessment of the functional significance of coronary lesions using a monorail catheter. J Invasive Cardiol 2001;13:279–86. PMID: 11287712.
  • Diletti R, on behalf of the Thoraxcenter Investigators: van Bommel R, Masdjedi K, van Zandvoort L, et al. Routine fractional flow reserve measurement after percutaneous coronary intervention: the FFR-SEARCH study. Presented at: EuroPCR, May 18 2017, Paris, France.
  • Diletti R, Van Mieghem NM, Valgimigli M, et al. Rapid exchange ultra-thin microcatheter using fibre-optic sensing technology for measurement of intracoronary fractional flow reserve. EuroIntervention 2015;11:428–32. DOI: 10.4244/ eijy15m05_09; PMID: 26013582.
  • Fearon WF, Chambers JW, Seto AH, et al FFR: Trials and new techniques. Primary Results of the Assessment of Catheter based Interrogation and Standard Techniques for Fractional Flow Reserve Measurement Study: The ACIST-FFR Study. Presented at: EuroPCR, May 16-19 2017, Paris.
  • Habib Samady, MD, Michael McDaniel, MD, Emir Veledar, PHD, Bernard De Bruyne, MD, PHD, Nico H. Pijls, MD, PHD, William F. Fearon, MD, Viola Vaccarino, MD, PHD* Baseline Fractional Flow Reserve and Stent Diameter Predict Optimal Post-Stent Fractional Flow Reserve and Major Adverse Cardiac Events After Bare-Metal Stent Deployment
  • Menon M, Jaffe W, Watson T, et al. Assessment of coronary fractional flow reserve using a monorail pressure catheter: the first-in-human ACCESS-NZ trial. Euro Intervention 2015;11:257–63. DOI: 10.4244/eijv11i3a51; PMID: 26196752.
  • Nico H.J. Pijls, Volker Klauss, Uwe Siebert, et al. Coronary Pressure Measurement After Stenting Predicts Adverse Events at Follow-Up: A Multicenter Registry, Circulation 2002;105:2950-2954; originally published online May 28, 2002;
  • Wolfrum M, Fahrni G, de Maria G, et al. Impact of impaired fractional flow reserve after coronary interventions on outcomes: a systematic review and meta-analysis, BMC Cardiovascular Disorders 2016 16:177,
  • Piroth Z, Toth G, Tonino P, et al. Prognostic Value of Fractional Flow Reserve Measured Immediately After Drug-Eluting Stent Implantation, Circulation: Cardiovascular Interventions 2017;10:e005233,


This webinar is supported by Acist