Michael D Shapiro

Michael D Shapiro

Director of the Center for Preventive Cardiology

Center for Prevention of Cardiovascular Disease, Section on Cardiovascular Medicine, Wake Forest University Baptist Medical Center, Winston-Salem, NC, US

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Personal History

Dr Shapiro lives in Winston-Salem with his wife and their two children. In his spare time, he enjoys travelling and hiking.


Academic History

Dr Shapiro completed medical school in 1998 at the UMDNJ School of Osteopathic Medicine. After completing a cardiology fellowship at the Beth Israel Medical Center, he spent two additional years in a clinical and research fellowship focused on advanced cardiovascular imaging at Massachusetts General Hospital / Harvard Medical School.


Career Overview

Dr Shapiro is the inaugural Fred M. Parrish professor of cardiology and molecular medicine at Wake Forest University. Previously, he was on the faculty in the Knight Cardiovascular Institute at Oregon Health & Science University. There, he was able to combine his interests in atherosclerosis imaging and the prevention of cardiovascular disease. He was director of atherosclerosis imaging and associate director of the Center for Preventive Cardiology.

Dr Shapiro’s clinical interests focus on genetic and acquired disorders of cholesterol and triglycerides, atherosclerosis imaging, genetic predisposition to early heart attacks and cardiovascular risk assessment in apparently healthy individuals. His work has been published extensively in the areas of atherosclerosis imaging, lipid disorders and preventive cardiology. Dr Shapiro’s current investigative research focuses on PCSK9 physiology and its impact on lipoprotein metabolism. Additionally, he is engaged in clinical trials testing novel lipid-modulating therapeutics.1


Career Timeline

  • 1998: Medical School, UMDNJ - School of Osteopathic Medicine
  • 1999 - 2002: Residency Internal Medicine, Beth Israel Medical Center
  • 2002 - 2005: Fellowship Cardiovascular Disease, Beth Israel Medical Center
  • 2005 - 2007: Fellowship Cardiac Imaging, Massachusetts General Hospital
  • Present: Director of the Center for Preventive Cardiology, Wake Forest Baptist Health



  • American Board of Internal Medicine, Cardiovascular Disease


Areas of Speciality

  • Cardiothoracic imaging
  • Preventive cardiology
  • Cardiovascular disease genetics
  • Exercise physiology and cardiac rehabilitation



  1. https://school.wakehealth.edu/Faculty/S/Michael-D-Shapiro 
  2. https://www.wakehealth.edu/Providers/S/Michael-D-Shapiro 


Articles by Michael D Shapiro, Director of the Center for Preventive Cardiology

The Role of Triglyceride-rich Lipoproteins and Their Remnants in Atherosclerotic Cardiovascular Disease

Mohanad Gabani , Michael D Shapiro, Peter P Toth, et al


Citation: European Cardiology Review 2023;18:e56.

Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition: The Big Step Forward in Lipid Control

Rishi Rikhi, Michael D Shapiro,


Citation: European Cardiology Review 2023;18:e45.

Inflammation and Cardiovascular Disease: The Future

Natalie Arnold, Katharina Lechner, Christoph Waldeyer, et al


Citation: European Cardiology Review 2021;16:e20.

Current Evidence and Future Directions of PCSK9 Inhibition

Jiaqian Xu, Michael D Shapiro,


Citation: US Cardiology Review 2021;15:e01.

Assessing Atherosclerotic Cardiovascular Disease Risk with Advanced Lipid Testing: State of the Science

Charles Amir German, Michael D Shapiro,


Citation: European Cardiology Review 2020;15:e56.

Emerging Strategies for the Management of Atherogenic Dyslipidaemia

Anandita Agarwala, Michael D Shapiro,


Citation: European Cardiology Review 2020;15:e05.