18
Jun
2025
15:30
BST
10:30
EDT
Webinar
Spotlight on Uncontrolled Hypertension: Assessing the Shift Towards Personalised Medicine – Part 2
00
Days
00
Hours
00
Mins
00
Secs
Faculty:
Sophia Ambruso
Paolo Mulatero
Overview
Join Dr Sophia Ambruso (University of Colorado, Denver, US) and Prof Paolo Mulatero (University of Torino, Turin, IT) for Part 2 of 'Spotlight on Uncontrolled Hypertension: Assessing the Shift Towards Personalised Medicine'. Together they will discuss how real-world evidence is reshaping the management of uncontrolled hypertension (HTN).
They will bring their real-world insights on aldosterone dysregulation and aggressive blood pressure lowering, including findings from the STEP trial. Looking ahead, we’ll examine emerging therapeutic targets, the limitations of mineralocorticoid receptor antagonists (MRAs), and novel approaches like nonsteroidal MRAs, endothelin receptor antagonists and angiotensinogen inhibition. Special focus will be given to aldosterone synthase inhibitors (ASIs), their mechanism of action and clinical data.
This programme is supported by an unrestricted educational grant from AstraZeneca.
Learning Objectives
- Understanding recent guideline recommendations
- Assessing cardiovascular risks of uncontrolled hypertension
- Understand pathophysiology with a focus on aldosterone’s role
- Examining novel therapeutic targets
- Cardiologists
- Hypertension Specialist
- Nephrologists
- Primary Care Physicians
- Pharmacists
- Healthcare Professionals
Faculty Biographies
Sophia Ambruso
Dr Sophia Ambruso is a Clinical Nephrologist and Assistant Professor at the Rocky Mountain VA Medical Center and University of Colorado School of Medicine, Denver, US. Dr Ambruso is passionate about patient care and medical education.
Paolo Mulatero
Prof Paolo Mulatero is Professor of Internal Medicine and Head of the Hypertension Unit, Department of Medical Sciences at the University of Torino, Turin, Italy.