The Relationship Between Hypertension and Cognitive Decline

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In the last 20 years, more than 700 papers were written about the relationship between hypertension and cognition. Hypertension precedes in more than 15 years the onset of dementia. The white matter lesions, the burden and his progression, are the most important risk factors for cognitive decline. This vascular brain injury negatively impacts on the frontal lobe and produces a disconnection between prefrontal cortex and the subcortical structures. The clinical expression of this damage is executive dysfunction, the most common cognitive domain affected. Twenty percent of the hypertensive patients with mild cognitive impairment, especially the non-amnestic form, it will develop Alzheimer dementia. The Alzheimer dementia is the most common type among hypertensive or patients with vascular disease. The early detection of the cognitive impairment and the antihypertensive treatment have and important role in the prevention of Alzheimer and vascular dementia.

Performed By:

Augusto Vicario

Augusto Vicario

Educational Objectives

  • The relationship between heart and brain
  • The impact of the hypertension on frontal lobe of the brain
  • The role of the antihypertensive treatment in the prevention of cognitive impairment and dementia
  • The importance of the early detection of the cognitive disorders in vascular patient

Target Audience

  • Cardiologists
  • Specialists in Internal Medicine
  • Neurologists
  • Psychiatrists

Faculty Biographies

Augusto Vicario

Augusto Vicario

Augusto Vicario is Clinical Cardiologist, graduated in Buenos Aires University and postgraduate in the El Salvador University, was Past President of the Buenos Aires Society of Cardiology (Argentine Federation of Cardiology) and Director of the “Heart and Brain Study”, a National Register of Cognitive Status in hypertensive patients. Today, he is full member of the Argentine Federation of Cardiology and of the Working Group “Hypertension and Brain” of the European Society of Hypertension. He develops his care task in the Heart and Brain Unit, Department of Clinical Cardiology of the Cardiovascular Institute of Buenos Aires, Argentina.

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Key References

1. Arterial Hypertension

2. Cognitive Impairment

3. Dementia

4. Alzheimer disease

5. Executive function

6. Frontal Lobe

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