Spotlight on Uncontrolled Hypertension: Assessing the Shift Towards Personalised Medicine – Part 1
Gain in-depth insights into the latest strategies for managing uncontrolled hypertension, guided by recent recommendations from the ESC, ESH, and KDIGO. Join Dr Jordana Cohen (Penn Medicine Hospital, Philadelphia, US) and Prof Kazem Rahimi (Oxford University Hospitals NHS Trust, Oxford, UK) as they explore different approaches to blood pressure control and evaluates the impact of key guidance documents, including the 2024 MASTERplan report.
Learning Objectives
- Understand and reflect on recent guideline recommendations for managing uncontrolled hypertension
- Assess the cardiovascular risks associated with uncontrolled hypertension
- Discuss the pathophysiology of resistant and uncontrolled hypertension with a focus on aldosterone's role
- Pharmacists
- Healthcare Professionals
Target Audience
- Cardiologists
- Hypertension Specialist
- Nephrologists
- Primary Care Physicians
More from this programme
Part 1
New Key Changes in Diagnosing Hypertension
Prof Kazem Rahimi and Dr Jordana Cohen explore key updates in the ESC hypertension guidelines, including the introduction of elevated blood pressure as a category, correct measurement techniques, and routine screening for primary aldosteronism. Watch to learn about key distinctions between ESC and other guidelines, emphasising early detection and risk assessment.
Part 2
The Role of RAAS in Hypertension and CKD
Dr Jordana Cohen explores the role of the RAAS system in hypertension and CKD, highlighting kidney-driven sodium and fluid retention. She discusses the toxic effects of aldosterone on the heart and kidneys, providing key insights into its impact on disease progression and potential treatment strategies.
Part 3
What Is Link Between Elevated BP and Renal Dysfunction?
Dr Jordana Cohen examines the bidirectional link between hypertension and kidney disease, highlighting its impact on other target organs, including the heart and brain. She explores how the combination of CKD and hypertension significantly increases cardiovascular risk, emphasizing the need for early intervention and effective management strategies.
Part 4
What is New in Hypertension Treatment?
Prof Rahimi and Dr Cohen discuss the latest advancements in hypertension management, from non-pharmacological strategies and combination therapy for non-resistant cases to specialist referrals and emerging treatments for resistant hypertension. They also explore the role of spironolactone, renal denervation, and the future potential of aldosterone synthase inhibitors (ASIs).
Part 5
Take Home Messages
Explore key takeaways from Prof Rahimi and Dr Cohen as they reflect on the discussion, highlighting essential insights on hypertension management, treatment strategies, and future advancements.
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Faculty Biographies
Kazem Rahimi
Kazem Rahimi is a Professor of Cardiovascular Medicine and Population Health, at the University of Oxford and a consultant cardiologist at the Oxford University Hospitals NHS Trust in Oxford, UK. His research interests include hypertension, heart failure, multimorbidity and cardiovascular risk management, using a variety of methodologies such as individual-patient meta-analysis, large-scale decentralised clinical trials, and digital health technologies.
Prof Rahimi leads the Deep Medicine programme at the Nuffield Department of Women’s and Reproductive Health with a major interest in application of machine learning approaches to electronic health records. He also leads the Blood Pressure Lowering Treatment Trialists’ Collaboration (BPLTTC), which is an international collaboration of all the major trials of blood pressure lowering drugs. He is the Director of the Martin School programme on Informal Cities and a Co-Investigator of the PEAK-Urban…
Jordana Cohen
Associate Professor of Medicine (Renal-Electrolyte and Hypertension)
Dr Jordana Cohen is an Associate Professor of Medicine in the Division of Renal-Electrolyte and Hypertension at the Hospital of the University of Pennsylvania and an Associate Professor of Epidemiology in Biostatistics and Epidemiology in Philadelphia, US. Dr Cohen specialises in renal and electrolyte disorders and hypertension management.
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