Spotlight on EAS: Precision Lipid Management

Spotlight on EAS: Precision Lipid Management

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About the episode

Prof Ulrich Laufs discusses new insights on muscle-related symptoms and patient-reported outcomes from the VICTORION-Difference study, including frequency and impact of muscle symptoms, effect on LDL-C goal attainment, and how these findings can help clinicians address tolerability concerns and support patient-centred lipid management.

Overview

This programme provides a focused spotlight on the latest developments and data presented at the European Atherosclerosis Society (EAS) Congress. Through a series of sessions, recorded at EAS and contributed by various faculty members, each offers concise analysis of late-breaking trial data, sub-analyses, and the clinical implications shaping contemporary lipid management.

 

Key Learning Objectives

  • Identify suitable patients for ApoC-III initiation using validated scoring parameters
  • Recall the most recent guidance for the use of ApoC-III inhibitor therapy
  • Discuss emerging clinical evidence of TG-lowering therapies across important trial sub-populations

Target Audience

  • Cardiologists
  • Lipidologists
  • Gastroenterologists
  • Endocrinologists
  • Other specialists associated with the management of familial chylomicronaemia syndrome (FCS)

More from this programme

Part 1

A Deep Dive Into the Data: Targeting ApoC-III Special Populations

The burden of hypertriglyceridemia (HTG) spans a broad and diverse patient population, from rare genetic disorders such as familial chylomicronaemia syndrome (FCS) to mixed hyperlipidaemia and familial dyslipidaemias. Current treatment strategies, including statins and fibrates, remain limited in their ability to adequately control triglyceride levels in many patients, highlighting the need for education around emerging therapeutic classes. ApoC-III–targeted therapies are demonstrating significant TG-lowering potential and are increasingly being evaluated across a wider range of patient populations, including those with FCS.


In this video, Dr Erin Michos (Johns Hopkins University School of Medicine, Baltimore, US) provides a deep dive into data presented at EAS 2026, targeting APOC-III in special populations.

 

This session is supported by an unrestricted educational grant from Arrowhead Pharmaceuticals.

Part 2

In Context: A Peer-To-Peer Discussion on ApoC-III in Special Populations and Other Emerging Data

The burden of hypertriglyceridemia (HTG) spans a broad and diverse patient population, from rare genetic disorders such as familial chylomicronaemia syndrome (FCS) to mixed hyperlipidaemia and familial dyslipidaemias. Current treatment strategies, including statins and fibrates, remain limited in their ability to adequately control triglyceride levels in many patients, highlighting the need for education around emerging therapeutic classes. ApoC-III–targeted therapies are demonstrating significant TG-lowering potential and are increasingly being evaluated across a wider range of patient populations, including those with FCS.

 

In this video, Dr Michos (Johns Hopkins University School of Medicine, Baltimore, US) is joined by Dr Christie Ballantyne (Baylor College of Medicine, Houston, US) for an in-depth discussion on real-world implications and clinical decision-making around applying emerging guidance and evidence in severe hypertriglyceridemia and FCS. They review evolving guidelines and what emerging data tells us about managing complex patient populations.

 

This session is supported by an unrestricted educational grant from Arrowhead Pharmaceuticals.

Faculty Biographies

Ulrich Laufs

Ulrich Laufs

Professor of Cardiology at Leipzig University

Ulrich Laufs is Chair and Professor of Cardiology at Leipzig University, Germany. Professor Laufs has published multiple experimental and clinical studies in the areas of ‘heart failure’, ‘heart and brain’ and ‘prevention’ with special interest in lipoprotein metabolism. He has received numerous honours, serves in several editorial boards of international cardiovascular journals and holds positions in cardiovascular societies.

 

 

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