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SCAI 25: AVENTUS Thrombectomy System: Autologous Blood Reinfusion for Pulmonary Embolism

Published: 12 May 2025

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SCAI 25 - Outcomes from the AVENTUS thrombectomy system for intermediate-risk pulmonary embolism show a significant improvement in right ventricular to left ventricular ratio reduction compared to the baseline measurements. The AVENTUS thrombectomy system also met the trial's safety outcome with no device-related major adverse events at 48 hours post-procedure.

We are joined by Dr Jun Li (University Hospitals Cleveland Medical Center, US) to discuss the findings from a prospective, pivotal, IDE trial investigating the next-generation AVENTUS thrombectomy system for intermediate-risk pulmonary embolism. The primary outcome measure was right ventricular to left ventricular ratio reduction at 40 hours post-procedure measured using a CT scan. The safety outcome was major adverse events related to the device at 48 hours post-procedure.

Interview Questions:
1. What is the importance of this research, and could you tell us about the AVENTUS Thrombectomy System?
2. What is the study design and patient population?
3. What were the key outcomes?
4. What are the implications for clinical practice?
5. What further study is required, and what are the next steps?

Recorded remotely from Ohio, 2025.


Editors: Jordan Rance, Yazmin Sadik
Videographers: David-Ben Harosh

Support: This is an independent interview produced by Radcliffe Cardiology. 

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