New York Valves 25 - Quantitative findings from Tri-QOL showed a strong correlation between tricuspid regurgitation (TR) reduction and KCCQ improvement after transcatheter tricuspid valve intervention (TTVI).

Dr Suzanne Arnold (Saint Luke's Mid America Heart Institute, Kansas City, US) discusses findings from a quantitative analysis from the Tri-QOL study which aimed to assess the optimal result for TTVI by investigating the association of change in KCCQ versus change in tricuspid regurgitation. Data sets from six single-arm studies investigating TR valve interventions were acquired from Edwards Lifescinces and Abbott, and about 1,000 patients with severe or greater TR who had received a valve intervention were analysed.

Findings showed that the more TR reduction observed, the more KCCQ improvement was achieved. However, in patients who started with torrential TR, a plateau in improvement in KCCQ was seen once they achieved a below moderate TR status.

Interview Questions:
1. What was the rationale behind this research?
2. What was the study design and the patient population?
3. What were the key findings?
4. How do you envision the results of the Tri-QOL study influencing future research or clinical practice regarding TTVI?
5. What further research questions remain?

Recorded remotely from Kansas City, 2025.

Editors: Jordan Rance, Yazmin Sadik
Videographers: David Ben-Harosh

Support: This is an independent interview produced by Radcliffe Cardiology.