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NY Valves 25: Lifetime Management in TAVR Patients

Published: 25 Jun 2025

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New York Valves 25 - Dr Tanush Gupta (UVM Medical Center, Burlington, VT, US) joins us to discuss key conversations around lifetime management for transcatheter aortic valve replacement (TAVR) patients. He discusses key data from the NOTION trial and how this has influenced his practice, as well emerging technologies such as AI simulation models and new valves.

Interview Questions:

  1. How has FDA approval for TAVR in asymptomatic severe aortic stenosis changed your lifetime management approach?
  2. How was 10-year follow-up data from the NOTION trial affected your management strategy in young patients with AS?
  3. Which emerging technologies are you prioritizing for long-term patient outcomes?
  4. What factors have influenced your bleeding management strategy over time?
  5. How has your multidisciplinary decision-making changed for complex lifetime management cases?
  6. How are you preparing for the next wave of TAVR innovations in lifetime valve management?

Recorded remotely from Vermont, 2025.

Editors: Yazmin Sadik, Jordan Rance
Videographer: David Ben-Harosh

Support: This is an independent interview produced by Radcliffe Cardiology.

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Wilhelm Mistiaen
5d
The notion trial relief heavily on Trifecta and Mitroflow valves which have been retracted because of suboptimal performance. Repetition of the trial with Carpentier-Edwards valve is appropriate for comparison with TAVI