Next Steps in Heart Failure: The Changing Paradigms in Therapy to the Unmet Needs

Published: 26 October 2022

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During this broadcast, "Next Steps in Heart Failure: The Changing Paradigms in Therapy to the Unmet Needs", Radcliffe Medical Education brings together a globally-renowned European and American faculty to participate in a roundtable discussion. The aim: to provide both a reflection on the HF landscape following published data at congress and to examine what future developments can be expected at forthcoming events via lively discussion and data presentations.


Dr Javed Butler (University of Mississippi Medical Center, US) leads proceedings, and is joined by Dr Clyde Yancy (Northwestern University Feinberg School of Medicine, US), Prof Faiez Zannad (Academic Hospital (CHU), Nancy, FR), and Prof Christiane Angermann (University Hospital of Würzburg, Würzburg, DE) for an insightful presentation and a discussion. 



This programme is supported by an educational grant from the Boehringer Ingelheim ​and Lilly Alliance.

Upon participation in the roundtable discussion physicians will be able to:

  • Recall the utility of EF in heart failure treatment, patient selection and treatment response
  • Identify alternative measures to EF for the purposes HF severity and therapeutic efficacy
  • Incorporate quality of life measures for assessing therapeutic efficacy in HF
  • Recall outcomes from heart failure trials from recent congress and publications and their impact on practice

This programme is intended to educate:

  • Global Heart Failure Physicians
  • General Cardiologists

More from this programme

Part 1

How Is the Landscape of HF Changing?

Dr Javed Butler introduces the programme and expands on three prevailing topics that have a crucial impact on the current HF field.

Part 2

A Changing Paradigm in the Progression of HF Therapy Initiation

Prof Christiane Angermann explores the progression of HF therapy initiation, focusing on early vs late treatment. She looks at mortality rate after hospitalisation, what are the main reasons for hospitalisation, how outcomes after acute cardiac decompensation have changed with the new paradigm. Prof Angermann looks at different trial results.

Part 3

Roundtable Discussion

In this roundtable discussion the faculty discuss about early treatment and what it means.

Part 4

An ESC 2022 Update: Relevant New Medical Data

Prof Faiez Zannad, in his presentation, looks at the new data that was discussed at ESC Congress 2022. In particular he focuses on the data from the DELIVER and EMPEROR trials and discusses the utility of Ejection Fraction.

Part 5

Applying the Guidelines in Clinical Practice

Dr Clyde Yancy presents the new Guidelines recently released by international health organisations such as the AHA, ACC, HFSA and ESC and how these guidelines can be used in daily clinical practice.

Part 6

Roundtable Discussion: QOL, Implementation in Practice and Future Trials

In this final roundtable discussion the faculty exchange insights and examine the issues related to quality of life.

Faculty Biographies

Javed Butler

Javed Butler

Professor of Medicine

Dr Javed Butler is President, Baylor Scott and White Research Institute, Senior Vice President for the Baylor Scott and White Health and Professor of Medicine at the University of Mississippi, US. He is board certified in cardiovascular medicine and advanced heart failure and transplant medicine. His research interests focus on clinical trials in patients with heart failure.

He serves on several national committees for the American College of Cardiology, American Heart Association, National Institutes of Health, and the Heart Failure Society of America. He is the recipient of the Simon Dack Award by the American College of Cardiology as well as the Time, Feeling, and Focus Award by the American Heart Association.

Prof Butler has authored more than 900 peer-reviewed publications. He serves on the editorial board of several peer reviewed cardiovascular journals and has been cited numerous times in America’s Best Doctors list.


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Clyde W Yancy

Clyde W Yancy

Chief of Cardiology

Dr Clyde W Yancy, is Vice-Dean of Diversity & Inclusion, Northwestern University, Feinberg School of Medicine in Chicago, US. He concomitantly serves as Chief of Cardiology at Northwestern University, Feinberg School of Medicine, and Associate Director of the Bluhm Cardiovascular Institute at Northwestern Memorial Hospital. He holds the Magerstadt Endowed Professor of Medicine Chair and also holds an appointment as Professor of Medical Social Sciences.

Dr Yancy’s research interests are heart failure, clinical guideline generation, outcomes sciences, personalized medicine, and health care disparities. He is extensively published with well over 600 peer-reviewed publications, an H-index of > 100 and annual recognition as one of the most highly cited scientific authors worldwide. Dr Yancy is Deputy Editor, JAMA Cardiology, and Senior Section Editor (Heart Failure), Journal of the American College of Cardiology (JACC). He serves on the editorial boards for…

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Faiez Zannad

Faiez Zannad

Professor of Therapeutics and Cardiology, Head of CIC

Dr Faiez Zannad is Professor of Therapeutics & Cardiology and Head of the Division of Heart Failure, Hypertension and Preventive Cardiology for the department of Cardiovascular Disease of the Academic Hospital (CHU) in Nancy and the Director of the Clinical Investigation Centre (Inserm-CHU).

Dr Zannad is currently the Chairman of the ESC Working group on Pharmacology and Drug Therapy as well as a Boardmember of the ESC Heart Failure Association. He is Past-President of the French Society of Hypertension. 

Dr Zannad is Co-Editor-in-Chief for Fundamental and Clinical Pharmacology, the official journal of the European Pharmacology Societies Federation (EUPHAR). He chairs and organises annual international meetings on CardioVascular Clinical Trials (CVCT) and on Biomarkers in Heart Failure.

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Christiane Angermann

Christiane Angermann


Prof Christiane E. Angermann is trained in Medicine/Cardiology in Munich. At the Munich Univ. Hospital, she established a Multidisciplinary Program for Advanced Heart Failure (HF)/HTX. In 2001, she became Professor of Medicine/Cardiology at Würzburg University, heading the Cardiology Division, Department of Medicine II. She is one of the 5 founders of the Comprehensive Heart Failure Center Würzburg (CHFC), became CHFC Director of Clinical Research in 2010, and is currently Senior CHFC Professor of Clinical Research in Cardiology/HF.

Her main interests are healthcare research, eHealth and telemedicine, multi-morbidity, heart-mind-body interactions and prevention of HF.

Prof Angermann is/was an EC/SC member and/or National Leader of multiple clinical trials, (e.g., REPORT-HF, MEMS-HF, PASSPORT-HF, EMPULSE), and acts as reviewer, Ed. Board member or Editor-in-Chief (Current Heart Failure Reports) for many journals.

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