Latest Innovations in Cardiovascular Imaging Software

Published: 27 July 2021

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Medical Imaging within the cardiovascular arena is constantly subject to changes and new innovations. Pie Medical Imaging (PMI) is a software company that strives to be a front runner in this field.

This page gives an overview of PMI’s latest software developments. 


The key learnings to be taken from the content herein are to understand:

  • The role of medical imaging in interventional cardiology
  • What is the added value of medical imaging pre-, peri- and post-percutaneous interventions?
  • How does medical imaging blend in the healthcare professional’s daily practice?


This page is designed for:

  • Interventional cardiologists
  • Cardiac Surgeons
  • Radiologists
  • Paediatric Cardiovascular Surgeons



  • Eric Van Belle
  • João L Cavalcante
  • Joost Daemen
  • Victoria Delgado
  • Kaneshka Masdjedi
  • Nicolas Van Mieghem


  • Darren Mylotte
  • Yoshinobu Onuma
  • Friso Rijnberg
  • Liesbeth Rosseel
  • Patrick W Serruys
  • Osama Soliman

More from this programme

Part 1

The Present and Future of vFFR – Clinical Validation and Live Cases (Webinar co-hosted by Siemens Healthineers)

Webinar co-hosted by Siemens Healthineers - Learn about the role of angiography-derived physiology CAAS vFFR, how it works, and how can you implement vFFR in your cathlab. Join a live case and experience how pre- and post-PCI vFFR measurement can help in clinical practice. Get more insights into the FAST study validation series and the outcomes of the recently published FAST II multicenter study. In this session the learning objectives are to differentiate Angio-based FFR and CAAS vFFR, understand how is vFFR clinically validated and how to implement vFFR in the cathlab (with pre-recorded cases as examples).

Part 2

State-of-the-Art Imaging for Mitral Valve Interventions

Watch this video with Dr Joao Cavalcante and Professor Nicolas Van Mieghem discussing the contemporary imaging modalities used for planning and guidance of transcatheter mitral valve interventions to better understand the importance of imaging in TVMR. This discussion’s learning objectives are to understand the current status of mitral valve device technologies and related imaging, get an overview of frequently used modalities before, during and after mitral interventions and to understand the tips and tricks and considerations with regards to good quality imaging and proper analysis.

Part 3

Native and Virtual TEE for Structural Heart Interventions

The treatment of structural heart disease using percutaneous techniques has evolve tremendously during the last years. Parallel to that also the related imaging techniques have changed and improved. One of those developments in imaging is the ability to predict optimal views to assess the right treatment and to ensure the best patient outcome. Nowadays, 3mensio Structural Heart has the ability to use standard CT data to predict the optimal TEE views that can be obtained during a structural heart interventions. From the CT data you can detect the esophagus trajectory and simulate the TEE probe. The simulation visualizes both the single- and biplane views of all the structures of the heart as normally shown on TEE images. The primary learning objective of this video is to view the use of imaging during structural heart interventions and to see how to simulate TEE images using CT data and its benefits.

Part 4

Role of MRI 4D Flow in Optimizing Fontan Circulation

From MRI 4D Flow it is possible to obtain 3-directional velocities within3D volume of interest during the cardiac cycle within one single acquisition. This enables the user to get access to unique insights in adverse flow patterns. This webinar dives into the clinical application and advantages of Caas MR 4D Flow. In this video series we investigate what can MRI 4D Flow bring us? Which clinical parameters can we derive from MRI 4D Flow? And how to interpret different MRI flow patterns within the patient’s anatomy.

Part 5

Quantification of Aortic Regurgitation Using Video Densitometry

A certain degree of aortic regurgitation (AR) is not infrequently encountered after standard aortic valve replacement, and reportedly more often following transcatheter aortic valve implantation. AR is regularly screened by eye-balling, which results in high inter- and intra-observer variability. Caas A-Valve is a state-of-the art video densitometric quantification software that allows physicians to quantify valvular and paravalvular regurgitation immediately in the cath lab directly after placing the valve. Together with the distinguished team from NUI Galway lead by Professor Patrick Serruys this webinar was hosted to explain about Caas A-Valve and its capabilities. Our primary learning objective from this session is how to objectively quantify Aortic Regurgitation in a cath lab setting?

Faculty Biographies

João L Cavalcante

João L Cavalcante

Director of Cardiac MRI and Structural CT Labs

Dr. João L. Cavalcante earned his medical degree the Universidade Federal do Ceará in Fortaleza, Brazil. He did his internal medicine residency, chief residency and cardiology fellowship training at Henry Ford Hospital in Detroit, Michigan with Level II training in nuclear cardiology. He completed a dedicated 2-year advanced cardiovascular imaging fellowship at the Cleveland Clinic obtaining COCATS Level III in Interventional Echo, Cardiovascular CT and Cardiac MRI.

He is the Director of Cardiac MRI and Structural CT Labs of Minneapolis Heart Institute at the Abbott Northwestern Hospital, the largest cardiology practice in the Twin Cities. He is the Scientific Director of the Cardiovascular Imaging Research Center and Core Lab. His passion and track record is in multimodality Imaging and focus on valve and structural heart disease.

He participated as a writing committee member for the CBCMR (CMR…

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Nicolas M Van Mieghem

Nicolas M Van Mieghem

Medical Director

Personal History

From an early age, Professor Nicolas Maria Van Mieghem decided to pursue a career that would help others. “I enjoy the feeling of being able to help someone or do something important for them. I wanted to enter a profession that would channel my energy— I was always a busy child,” he says. 

A budding athlete, he was a member of Belgium’s national swimming team but soon realized that medicine was his true calling. His father was a general cardiologist and one of his biggest influences early in his career.

Professor Van Mieghem initially intended to train as a cardiac surgeon but decided to specialise in interventional cardiology instead, following advice from a mentor. This decision was cemented when he read the first-in-human case report of transcatheter aortic valve implantation (TAVI) in Circulation by Alain Cribier in 2002. 

His mantra is mens sana in corpore sano (a…

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