Individualising Antithrombotic Strategies for Established Coronary Artery Disease

Published: 07 March 2023

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    Part 1 Summary Marco Valgimigli
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In this on-demand version of the live broadcast, Radcliffe Medical Education bring together an expert panel to address the importance of providing individualised antithrombotic treatment in Acute Coronary Syndrome (ACS) and Chronic Coronary Syndrome (CCS). 


Chaired by Prof Marco Valgimigli (Instituto Cardiocentro Ticino, Lugano, CH), the panel review the two patient cases presented in phase one of this programme, present impactful new trial data, and discuss practical solutions to common challenges experienced in real-world practice.


Further, the faculty review and summarise the new recommendations for antithrombotic treatment strategies in ACS and CCS patients with established coronary artery disease (CAD) made in the 2022 joint clinical consensus statement of the European Association of Percutaneous Coronary Intervention (EAPCI), Association for Acute Cardiovascular Care (ACVC) and European Association of Preventive Cardiology (EAPC).


Note, the live version of this broadcast was CME accredited; this on-demand version is not.

This programme is supported by an unrestricted educational grant from AstraZeneca.

Learning Objectives

  • Summarise current guidance for choosing antithrombotic therapy in established CAD
  • Describe current gaps in clinical evidence and what is missing from current guidance
  • Adopt an evidence-based approach for managing patients with ACS and CCS

Target Audience

  • General Cardiologists
  • Interventional Cardiologists
  • Nurses
  • HCPs

More from this programme

Part 1


Join Prof Valgimigli as he provides an overview and summary of the following broadcast in this short and concise video.

1 session
Summary Watch now

Part 2

Patient Cases Revisited

Join Prof Navarese and Prof Vranckx as they present the two clinical case studies on ACS and CCS to be examined in this programme. Additionally, the panel review audience poll results on the initial approach to these patients.

Part 3

Development of a Consensus for Antithrombotic Therapy in CAD

Here Prof Valgimigli discusses the rationale behind the development of the new consensus statements on ACS and CCS, presents key data that has driven the recommendations, and highlights the shift in antiplatelet paradigm the consensus brings.

Part 4

Antithrombotic Treatment Strategies in Patients With Established CAD: Results of Two Network Meta-Analyses

Prof Navarese presents the results of a companion network meta-analysis on antithrombotic strategies in established CAD, including a ranking of individual strategies to identify best-in-class agents for key primary and secondary endpoints.

Part 5

Clinical Consensus Statements on Patients With ACS

Prof Kunadian summarises the recommendations made in the new joint clinical consensus statement of the EAPCI, ACVC and EAPC on patients with ACS, covering short and long-term strategy for monotherapy and dual/triple antiplatelet therapy.

Part 6

Clinical Consensus Statements on Patients With CCS

Prof Vranckx summarises the recommendations made in the new joint clinical consensus statement of the EAPCI, ACVC and EAPC on patients with CCS, covering individualised antithrombotic approaches and examination of bleeding risk.

Part 7

Panel Discussion and Q&A

Chaired by Prof Valgimigli, the faculty join to discuss the key learning points of the broadcast, answer audience questions and provide their expert opinion on the exemplar case studies.

Faculty Biographies

Marco Valgimigli

Marco Valgimigli

Deputy Chief of Cardiology

Prof Marco Valgimigli is an Interventional Cardiologist and Deputy Chief of Cardiology at the Cardiocentro Ticino Institute in Lugano, Switzerland.

He obtained his medical degree from the University of Bologna, and completed his training in internal medicine at the same university. He received a degree in cardiological sciences at the University of Ferrara and a PhD in interventional cardiology at Erasmus Medical Center in Rotterdam.

Prof Valgimigli’s areas of research are wide ranging and include high-risk percutaneous interventions (PCI); invasive treatment of myocardial ischaemia (MI); reparative medicine with adult stem cells during MI and heart failure; antithrombotic therapy during and after PCI; and prognostic stratification during acute coronary syndromes and MI.

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Eliano Navarese

Eliano Navarese

Director, Interventional Cardiology and Cardiovascular Medicine Research

Prof Eliano Navarese is associate Professor and Director of Research at the Cardiovascular Institute, Nicolaus Copernicus University, Poland and adjunct professor at University of Alberta, Canada.

His expertise is in the fields of interventional cardiology, coronary artery disease, antithrombotics, lipid-lowering therapies, cardiovascular pharmacotherapy, clinical trials and evidence-based medicine.

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Vijay Kunadian

Vijay Kunadian

Professor of Interventional Cardiology

Prof Vijay Kunadian is Personal Chair and Professor of Interventional Cardiology at Newcastle University. 

Prof Kunadian completed all her cardiology training in the North East of England. She undertook an international academic fellowship in cardiology at the TIMI/PERFUSE Study group, Brigham and Women’s Hospital/Harvard Medical School, Boston MA.

Prof Kunadian has an international reputation in interventional cardiology and cardiovascular research, making her a sought-after and respected speaker at prominent national and international meetings. She has championed diversity in her specialty as a role model; only 5% of interventional cardiologist are female in the UK, <1% are clinical academics.



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Pascal Vranckx

Pascal Vranckx

Clinical Consultant in Interventional Cardiology and Medical Director of Cardiac Critical Care Services

Prof Pascal Vranckx is a Clinical Consultant in Interventional Cardiology and Medical Director of Cardiac Critical Care Services at the Hartcentrum Hasselt in Belgium, and Professor of Medicine at the University of Hasselt, Belgium.

Prof Vranckx is also board member of the European Cardiovascular Research Institute, in Rotterdam, The Netherlands. 

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