Evolving Strategies in Pulmonary Embolism: From Risk Stratification to Interventional Therapy

  • Published:  08 December 2025
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    Welcome and Introduction
    Stavros Konstantinides, José M Montero-Cabezas, Mario Iannaccone, Sylwia Sławek-Szmyt
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Evolving Strategies in Pulmonary Embolism: From Risk Stratification to Interventional Therapy

  • Published:  08 December 2025
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Overview

This expert-led, on-demand programme explores the latest evidence and interventional strategies for intermediate-high and high-risk pulmonary embolism (PE). Chaired by Prof Stavros Konstantinides (University of Mainz, Mainz, DE) and featuring renowned specialists Dr José Montero-Cabezas (Leiden University Medical Center, Leiden, NL), Dr Mario Iannaccone (Turin Nord Emergency Hospital, Turin, IT) and Dr Sylwia Sławek-Szmyt (Poznan University of Medical Sciences, Poznan, PL), this session delivers a comprehensive, clinically relevant update on the evolving landscape of PE care.

 

The session offers a comprehensive exploration of risk stratification and clinical decision-making in pulmonary embolism care. Gain clinical trial insights through an in-depth look at the STORM-PE and STRIKE-PE trials, examining their findings and how they shape current practice. A dedicated technology spotlight provides a detailed review of Computer Assisted Vacuum Thrombectomy (CAVT), followed by case-based learning that showcases real-world CAVT interventions, including technique considerations, clinical outcomes, and post-procedural care. The session concludes with an interactive panel discussion.

 

Learn at your own pace and access expert insights and real-world clinical examples. 

 

This programme is supported by Penumbra, Inc.

Key Learning Objectives

  • Understand the clinical presentation and risk stratification of intermediate-high and high- risk pulmonary embolism, with emphasis on indicators for escalation to advanced interventional therapies
  • Evaluate current evidence and emerging clinical trial data, including STRIKE-PE and STORM- PE, supporting the use of Computer Assisted Vacuum Thrombectomy in the management of acute pulmonary embolism
  • Review the technical considerations and procedural workflow of Computer Assisted Vacuum Thrombectomy including patient selection, access strategy and safety outcomes
  • Apply real-world clinical experience through case-based learning, illustrating decision- making, procedural technique and post-procedural care in PE patients treated with catheter-based interventions
  • Engage in multidisciplinary discussion to refine treatment strategies, enhance guideline- concordant care

Target Audience

  • Interventional Cardiologists
  • Interventional Radiologists
  • Angiologists
  • Intensive Care Unit
  • General Cardiologists
  • Pneumologists

More from this programme

Part 1

Welcome and Introduction

Prof Konstantinides provides a short overview and introduction to the webinar.

Part 2

Risk-Adjusted Assessment: Who Needs Advanced Treatment?

Dr José Montero-Cabezas presents on distinguishing between intermediate-high vs high-risk PE patients, patient selection for advanced therapies, and the importance of the collaboration of PERT teams.

Part 3

Principles and Practice of Computer Assisted Vacuum Thrombectomy

Dr Mario Iannacone discusses Computer-Assisted Vacuum Thrombectomy (CAVT), using a a clinical presentation of a 71-year-old male. 

Part 4

Evidence and Emerging Data

Prof Stavros Konstantinides provides an overview of STRIKE-PE and STORM-PE trial findings. 

Part 5

Clinical Application: Real-Life Case Series

Dr Sylwia Sławek-Szmyt shares two PE case studies treated with Computer Assisted Vacuum Thrombectomy.

Part 6

Panel Discussion & Audience Q&A

Prof Stavros Konstantinides chairs an engaging panel discussion, guiding an interactive session where key questions from the live audience are addressed. 

Faculty Biographies

Stavros Konstantinides

Stavros Konstantinides

Professor for Clinical Trials and Medical Director of the Center for Thrombosis and Hemostasis

Prof Stavros Konstantinides, MD, FESC, is Professor for Clinical Trials and Medical Director of the Center for Thrombosis and Hemostasis (CTH) at the University of Mainz, Germany. He is also Professor of Cardiology at the Democritus University of Thrace, Greece. He graduated from the Aristotle University of Thessalonica, Greece, and earned his doctorate degree at the University of Freiburg, Germany. 

For the past 35 years, his clinical and translational research has focused on the risk stratification and risk-adapted antithrombotic management of thrombosis and pulmonary embolism. He has designed and coordinated, and has been principal investigator of numerous high-impact national and international academically sponsored multicentre trials. He is leading member of national and European committees, task forces for clinical practice guidelines, and of networks on pulmonary circulation and right ventricular function.

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José M Montero-Cabezas

José M Montero-Cabezas

Interventional Cardiologist

Dr José Montero-Cabezas is an interventional cardiologist at Leiden University Medical Center (LUMC), Netherlands. He completed his cardiology training at the 12 de Octubre University Hospital (Complutense University, Madrid), followed by a fellowship in interventional cardiology at LUMC. He holds a PhD from Leiden University, a Master’s degree in Healthcare Management and Administration from CEU University (Spain), and completed a postgraduate program in Clinical Research at Harvard Medical School (USA).

Dr Montero-Cabezas has a particular clinical and research interest in complex percutaneous coronary interventions (with a focus on chronic total occlusions), mechanical circulatory support, invasive therapies for acute pulmonary embolism, and structural heart interventions such as TAVI.

He is a co-founder and core member of the LUMC Shock Team, a multidisciplinary group dedicated to the management of cardiogenic shock, and of ALERT (Acute Pulmonary Embolism Response…

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Mario Iannaccone

Mario Iannaccone

Interventional Cardiologist

Dr Mario Iannaccone is an interventional cardiologist in Turin Nord Emergency Hospital, Turin, Italy. He received his MD from the University of Neaples in 2010. He completed his clinical and research fellowship in cardiology at Turin University Hospital in 2017 and developed his skills in complex coronary interventions at the San Giovanni Bosco Hospital (Turin) under the mentorship of Dr Roberto Garbo. 
 
His main fields of interest are complex coronary intervention, chronic total occlusion recanalisation, intracoronary imaging, cardiogenic shock, mechanical support devices and pulmonary embolism. Dr Iannaccone has authored about 170 publications on those topics.

Dr Iannaccone is a member of the editorial board for Interventional Cardiology: Reviews, Research, Resources.

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Sylwia Sławek-Szmyt

Sylwia Sławek-Szmyt

Interventional Cardiologist

Sylwia Sławek-Szmyt is an Assistant Professor and Consultant Cardiologist at the Department of Cardiology, Poznan University of Medical Sciences, Poland, with a focus on interventional cardiology and pulmonary embolism care. She leads the outpatient clinic for patients after pulmonary embolism and performs a wide range of catheter-based coronary, structural, and pulmonary vascular interventions. Her clinical practice is complemented by active involvement in international fellowships, including structural interventions training in Katowice and interventional cardiology at Heart Center Dresden. She is a Fellow of the European Society of Cardiology and an active member of multiple ESC working groups and EAPCI committees.

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