ESC Congress 2025 Hot Line & Late-Breaking Science Collection

  • Published:  08 August 2025
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ESC Congress 2025 Hot Line & Late-Breaking Science Collection

  • Published:  08 August 2025
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About the episode

ESC Congress 2025 - Long-term beta-blocker therapy after myocardial infarction reduced the primary endpoint of death from any cause or major adverse cardiovascular events.

Late-breaker host Dr Harriette Van Spall (McMaster University, CA) sits down with Prof Dan Atar (Oslo University Hospital Ulleval, NO) and Dr Anna Meta Dyrvig Kristensen (Bispebjerg and Frederiksberg Hospital, DK) to discuss the latest findings from the combined BETAMI-DANBLOCK trial evaluating beta-blocker therapy after myocardial infarction.

This landmark event-driven trial represents the largest modern evaluation of beta-blocker efficacy in post-MI patients, combining the Danish DANBLOCK and Norwegian BETAMI studies to randomise approximately 5,700 patients with normal or mildly reduced left ventricular ejection fraction (LVEF ≥ 40%) to open-label beta-blocker therapy or no such treatment.

Findings presented first at ESC.25 showed that when administered within 14 days of MI, long-term beta-blocker therapy was found to reduce death from any cause or major adverse cardiovascular events.

Recorded onsite at ESC Congress 2025 in Madrid.

Editors: Jordan Rance and Yazmin Sadik.
Videographers: Mike Knight, Dan Brent, Oliver Miles, Tom Green, David-Ben-Harosh.

Support: This is an independent interview produced by Radcliffe Cardiology. 

Overview

Dive into our coverage of ESC Congress 2025 for groundbreaking trial results and discussions with expert faculty.

  • Watch our View From the Thoraxcenter series for practice-focused reviews of the most anticipated trials from interventional experts, Prof Nicolas Van Mieghem and Dr Joost Daemen.
  • Watch our Wrap-Up series led by Dr Mirvat Alasnag summarising the key take-aways from each day of the congress.
  • For clinical trial data from principal investigators, keep up with Dr Harriette Van Spall's Late-Breaker Discussion series.
  • Our concise, accessible Expert Interviews will focus on the current data and it's impact on clinical practice.
  • Don't miss the Highlights series to stay ahead of the curve in each field.
  • In the Journal Discussions series, authors of ECR Journal explore their special focuses in depth.
     

More from this programme

Faculty Biographies

Harriette Van Spall

Harriette Van Spall

Associate Professor of Medicine, Director of E-Health and Virtual Care

Dr Harriette Van Spall is an internationally-known cardiologist, research methodologist, and senior scientist. Trained at the University of Toronto and Harvard University, she has expertise in clinical trial design and execution. Her investigator-initiated research is well funded and has been recognised formally with the American Heart Association's Nanette Wenger Research Goes Red award and the Canadian Institutes of Health Research Mid-Career Lectureship award.

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Dan Atar

Dan Atar

Professor of Cardiology

Prof Dan Atar is Head of Research and Professor of Cardiology at the University of Oslo, Oslo, NO. He studied medicine in Basel and was then trained in internal medicine and cardiology.

Prof Atar joined John Hopkins University in Baltimore (1991–1994) and the University of Copenhagen, where he worked as a senior cardiologist. From 1997 to 1998 Dan Atar served as senior physician, supported by the Cloëtta Foundation of Cardiology at the University Hospital of Zurich.

Prof Atar has written over 480 articles and book chapters (H-index 78) and holds the fellowship-titles FESC, FACC, FEHRA and inaugural FAHA. He served as Chairman of the ESC Working Group on Cardiovascular Pharmacotherapy. He was on several ESC guideline writing committees, amongst others the 2010, 2012 and 2016 ESC Guidelines on Atrial Fibrillation, the 2012 STEMI-Guidelines and the 2018 Universal Definition of AMI. In 2012 Professor Atar was elected as Councilor and Board member, in 2014 as Vice…

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Anna Meta Dyrvig Kristensen

MB

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