ESC Congress 2025 Hot Line & Late-Breaking Science Collection

  • Published:  08 August 2025
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ESC Congress 2025 Hot Line & Late-Breaking Science Collection

  • Published:  08 August 2025
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About the episode

ESC Congress 2025 - Paclitaxel-coated devices in critical limb threatening ischemia were not effective in preventing amputation, nor improving quality-of-life in intermittent claudication.

Dr Mårten Falkenberg (Sahlgrenska University Hospital, Gothenburg, SE) and Prof Joakim Nordanstig (Sahlgrenska University Hospital, Gothenburg, SE) join us to discuss findings from the SWEDEPAD 1 and 2 parallel studies. The multicenter, prospective, randomised trial investigated the impact of drug-coated devices in patients with PAD based on the Swedish Vascular Registry Platform. Patients with critical limb ischemia were enrolled to SWEDEPAD 1 and patients with intermittent claudication were enrolled to SWEDEPAD 2.

Findings showed that in both CLTI and intermittent claudication, paclitaxel coated devices were not associated with reduced risk of amputation or improved quality of life compared to uncoated devices.

Interview Questions:

  1. What is the reasoning behind SWEDEPAD 1 and 2?
  2. What was the study design and patient population?
  3. What were the key findings?
  4. What are the take-home messages for practice?
  5. What further research is needed in this area?

Recorded on-site at ESC Congress 2025, Madrid.

Editors: Jordan Rance, Yazmin Sadik.
Videographers: Mike Knight, Dan Brent, Oliver Miles, Tom Green, David-Ben-Harosh.
Support: This is an independent interview produced by Radcliffe Vascular.

Overview

Dive into our coverage of ESC Congress 2025 for groundbreaking trial results and discussions with expert faculty.

  • Watch our View From the Thoraxcenter series for practice-focused reviews of the most anticipated trials from interventional experts, Prof Nicolas Van Mieghem and Dr Joost Daemen.
  • Watch our Wrap-Up series led by Dr Mirvat Alasnag summarising the key take-aways from each day of the congress.
  • For clinical trial data from principal investigators, keep up with Dr Harriette Van Spall's Late-Breaker Discussion series.
  • Our concise, accessible Expert Interviews will focus on the current data and it's impact on clinical practice.
  • Don't miss the Highlights series to stay ahead of the curve in each field.
  • In the Journal Discussions series, authors of ECR Journal explore their special focuses in depth.
     

More from this programme

Faculty Biographies

Marten Falkenberg

Marten Falkenberg

Associate Professor of Vascular Surgery

View full profile
Joakim Nordanstig

Joakim Nordanstig

Associate Professor of Vascular Surgery

View full profile
GA statistics 30d
93
GA statistics all time
3002

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