ESC Congress 2025 Hot Line & Late-Breaking Science Collection

  • Published:  08 August 2025
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ESC Congress 2025 Hot Line & Late-Breaking Science Collection

  • Published:  08 August 2025
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About the episode

ESC Congress 2025 - FARADISE Registry finds FARAPULSE™ pulsed field ablation (PFA) system safe and easy to use, with an 80% clinical effectiveness at one year in paroxysmal AF.

Prof Lucas Boersma (St Antonius Hospital, Nieuwegein, NL) joins us to discuss one-year findings from the observational, prospective, single-arm FARADISE global registry (NCT05501873) which collected real-world data from up to 100 sites in Europe to investigate the clinical effectiveness of the FARAPULSE™ Pentaspline PFA system.

The registry found that the PFA system was safe and easy to use, with a low event rate of 1.5% at one year. In terms of effectiveness, at one year clinical effectiveness is around 80% for paroxysmal AF, and around 70% for persistent AF.

Interview Questions:

  1. What is the reasoning behind the FARADISE global registry?
  2. Could you tell us about the unique features of the FARAPULSE™ PFA system?
  3. What was the study design and patient population?
  4. What are the key findings?
  5. What are the take-home messages for practice, and what are the next steps?

Recorded on-site at ESC Congress 2025, Madrid.

Editors: Jordan Rance, Yazmin Sadik.
Videographers: Mike Knight, Dan Brent, Oliver Miles, Tom Green, David-Ben-Harosh.
Support: This is an independent interview produced by Arrhythmia Academy.

Overview

Dive into our coverage of ESC Congress 2025 for groundbreaking trial results and discussions with expert faculty.

  • Watch our View From the Thoraxcenter series for practice-focused reviews of the most anticipated trials from interventional experts, Prof Nicolas Van Mieghem and Dr Joost Daemen.
  • Watch our Wrap-Up series led by Dr Mirvat Alasnag summarising the key take-aways from each day of the congress.
  • For clinical trial data from principal investigators, keep up with Dr Harriette Van Spall's Late-Breaker Discussion series.
  • Our concise, accessible Expert Interviews will focus on the current data and it's impact on clinical practice.
  • Don't miss the Highlights series to stay ahead of the curve in each field.
  • In the Journal Discussions series, authors of ECR Journal explore their special focuses in depth.
     

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Faculty Biographies

Lucas Boersma

Lucas Boersma

Cardiac Electrophysiologist

Prof Lucas Boersma is a cardiologist/electrophysiologist at St. Antonius Hospital Nieuwegein and a Professor of Cardiology at the University of Amsterdam, NL. In his research, Prof Lucas Boersma has primarily focused on transcatheter treatment of atrial fibrillation. Prof Lucas Boersma is the chairman of the Netherlands Society of Cardiology (NVVC) Knowledge Agenda Committee.

Prof Boersma graduated from Medical School in 1996 at the University of Maastricht. In the same year he finished his PHD on Ventricular Tachycardia in the Rabbit Heart. He completed his Cardiology specialty training in 2000 at St. Antonius Hospital in Nieuwegein and his subspecialty training in Electrophysiology in 2001 at Hospital Clinic in Barcelona, ES. He was Head of the Cardiology Department from 2008-2016, as well as Medical Manager of the Cardiovascular Unit from 2011-2017.

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