Pacing, Defibrillators & Cardiac Resynchronisation Therapy

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Anisotropic Cardiac Conduction

Irum D Kotadia, John Whitaker, Caroline H Roney, et al

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Intraventricular Conduction Disturbances After TAVI

Shu-I Lin, Mizuki Miura, Ana Paula Tagliari, et al

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Radiation Exposure in Electrophysiology and Interventional Cardiology

Deepak Padmanabhan, Sandeep Shankar, Avinash Chandrashekharaiah, et al

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Improving Cardiac Resynchronisation Therapy

George Thomas, Jiwon Kim, Bruce B Lerman,

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Update in Cardiac Pacing

Nishant Verma, Bradley P Knight,

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Pacemaker and Defibrillator Implantation and Programming

Mark Elliott, Sheikh Momin, Barnaby Fiddes, et al

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Syncope and Cardiac Arrhythmias

Andrei D Mărgulescu, Mark H Anderson,

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Cardiac Resynchronisation Therapy and Cellular Bioenergetics

Christos-Konstantinos Antoniou, Panagiota Manolakou, Nikolaos Magkas, et al

About

Cardiac pacing is a well-established therapeutic tool improving the survival and quality of life in patients. Indications for permanent cardiac pacing include sinus node dysfunction, intermittent and incomplete atrioventricular block, and bundle branch block.

Cardiac pacing, in conjunction with beta-blocker therapy, can potentially reduce the risk of bradycardia-dependent QT prolongation, decrease heart-rate irregularities and reduce repolarisation heterogeneity.

Cardiac resynchronisation therapy (CRT) with biventricular pacing is an effective therapy in patients with advanced heart failure (HF) – New York Heart Association (NYHA) Class III or IV, an ejection fraction (EF) 120 ms.

CRT has also been shown to be effective for the prevention of HF in relatively asymptomatic patients with wide QRS. However, CRT is underutilised among eligible patients. Approximately one-third of patients do not respond to CRT due to various factors, including anatomic difficulties and suboptimal lead placement. To increase the effectiveness of CRT, it has been hypothesised that pacing at multiple left ventricular (LV) sites may provide more effective resynchronisation.

In clinical studies, use of MultiPoint pacing in HF patients undergoing CRT has been associated with increased haemodynamic and clinical benefits compared with conventional pacing, particularly in patients with the least improvement from biventricular pacing.

Related Articles

Articles

Article icon
Anisotropic Cardiac Conduction

Published: - Irum D Kotadia, John Whitaker, Caroline H Roney,

Citation: Arrhythmia & Electrophysiology Review 2020;9(4):202–10.

Intraventricular Conduction Disturbances After TAVI

Published: - Shu-I Lin, Mizuki Miura, Ana Paula Tagliari,

Citation: Interventional Cardiology Review 2020;15:e11.

Heart Failure Treatment by Device

Published: - Antoni Bayés-Genís,

Citation: European Cardiology Review 2020;15:e17.

Radiation Exposure in Electrophysiology and Interventional Cardiology

Published: - Deepak Padmanabhan, Sandeep Shankar, Avinash Chandrashekharaiah,

Citation: US Cardiology Review 2019;13(2):117–22.