Search results
Author(s):
David S Celermajer
Added:
3 years ago
In 1953, Enos and colleagues published the then extraordinary finding that coronary artery atheroma could be found in the majority of young US soldiers killed in action during the Korean war.1 This finding has since been replicated by other pathologists who not only documented a high prevalence of aortic and coronary atherosclerosis in teenagers and young adults, but also linked the amount of…
View more
Author(s):
Olivia Manfrini
,
Peter Amaduzzi
,
Maria Bergami
,
et al
Added:
3 years ago
Statins are commonly used in patients with hypercholesterolaemia and in those with cardiovascular diseases – that is, peripheral artery disease and coronary artery disease (CAD) – for the prevention of atheromatous plaque development, progression and complications, with the aim of reducing subsequent major adverse cardiovascular events (MACE), i.e. cardiac death, acute MI, stroke and heart…
View more
Author(s):
Seung Hwan Han
,
Kwang Kon Koh
Added:
3 years ago
Systemic hypertension, hypercholesterolaemia and diabetes are associated with endothelial dysfunction that promotes inflammation, oxidation of lipoproteins, smooth-muscle proliferation, extracellular matrix deposition or lysis, accumulation of lipid-rich material, platelet activation, thrombus formation and insulin resistance. All of these consequences of endothelial dysfunction and insulin…
View more
Author(s):
Paul M Vanhoutte
Added:
3 years ago
More than a quarter of a century ago Robert Furchgoldltt demonstrated that removing the endothelial layer from the isolated aorta of a rabbit prevents normal relaxation in response to acetylcholine.1 The ability of the endothelium to elicit relaxation was soon extended to more relevant physiological stimuli (adenosine triphosphate, bradykinin and serotonin).2,3 The endothelial cells cause…
View more
Author(s):
Maria Teresa Bayo Jimenez
,
Omar Hahad
,
Marin Kuntic
,
et al
Added:
11 months ago
Added:
3 years ago
Prolonged sitting is potentially damaging to the arteries but a new study published inMedicine & Science in Sports & Exercise, the official journal of the American College of Sports Medicine, reveals that it can be easily reversed with hourly 5-minute walks.
Sitting for long periods of time is associated with risk factors such as higher cholesterol levels and greater waist circumference that can…
View more
Author(s):
Andrea Aparicio
,
Javier Cuevas
,
César Morís
,
et al
Added:
2 years ago
Gaetano Antonio Lanza
Research Area(s) / Expertise:
Job title: Associate Professor
Author
Thomas Kahan
Research Area(s) / Expertise:
Author
Giuseppe Rosano
Research Area(s) / Expertise:
Job title: Consultant Cardiologist and Professor of Cardiology (Hon)
Author