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PROMOTED
Author(s):
Nicolas M Van Mieghem
,
Kendra J Grubb
,
David Hildick-Smith
,
et al
Start date:
Mar 26, 2024
Author(s):
Tom Ford
,
Colin Berry
Added:
3 years ago
Ischaemic heart disease persists as the leading global cause of death and lost life years in adults.1 Angina is a common clinical presentation of ischaemic heart disease related to a supply:demand mismatch of myocardial blood flow, typically provoked by exertion or stress. Invasive coronary angiography is the reference test for angina and identifies obstructive coronary artery disease (CAD) as a…
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Author(s):
Alda Huqi
,
Giacinta Guarini
,
Doralisa Morrone
,
et al
Added:
3 years ago
Myocardial revascularisation in patients with stable chronic angina is performed with the aim of reducing cardiovascular death, reducing myocardial infarction (MI) and relieving angina symptoms. However, contrary to expectations, modern therapy with percutaneous coronary intervention (PCI) has not had a significant impact on hard outcomes.1–5 Indeed, as also summarised in a recently published…
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Author(s):
Gaetano Antonio Lanza
Added:
3 years ago
Up to 50% of patients who undergo elective coronary angiography for stable chest pain symptoms that are mainly related to exercise and typical enough to suggest the presence of obstructive coronary artery disease (CAD) are found to have normal or near-normal coronary arteries.1 The mechanisms responsible for angina chest pain in these patients are heterogeneous; accordingly, their identification…
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Author(s):
Kerry Layne
,
Albert Ferro
Added:
3 years ago
Acute coronary syndrome (ACS) is a term used to encompass unstable angina (UA) and myocardial infarction (MI) with or without electrocardiographic (ECG) evidence of ST-segment elevation. Antiplatelet therapy has formed the backbone of ACS management for decades and the drug class continues to evolve as novel agents with increasingly efficacious antiplatelet actions are identified. The main risk…
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Author(s):
Richard Solomon
Added:
3 years ago
The Problem of Contrast-induced Nephropathy
Contrast-induced nephropathy (CIN) is an increasingly common cause of acute renal failure in both hospitalized patients and out-patients. The growth in contrast-enhanced imaging and interventional procedures is one cause of the increased incidence of CIN. An aging patient population, with more comorbidities such as reduced renal function, may be…
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Author(s):
Alex J Auseon
Added:
3 years ago
In 2000, Drs Hill and Kerber, then of the University of Iowa Fellowship Training Program, published a manuscript exploring the state of specialty training in cardiology both nationally and at their institution.1 They described a comprehensive self-evaluation of their program and their approach to managing the many challenges faced by academic medical centers and cardiology faculties when training…
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Author(s):
Daniel A Goor
,
Samuel Sclarovsky
Added:
3 years ago
According to Myerburg and Costellanos, the introduction of cardiac revascularization to medicine (coronary artery bypass grafting [CABG]) almost 50 years ago led to a decline in the age-adjusted mortality from coronary artery disease (CAD),1 but brought no change to the fraction of coronary deaths that are sudden and unexpected.1 Of the 650,000 who die annually in the US of CAD, 300,000–350,000…
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Author(s):
Hartika Safitri
,
Amir Aziz Alkatiri
,
Doni Firman
,
et al
Added:
8 months ago
Author(s):
Abdulah Alrifai
,
Mohamad Kabach
,
Jonathan Nieves
,
et al
Added:
3 years ago
More than 10 million Americans suffer annually from angina.1 For decades, most of the attention has been focused on epicardial coronary artery disease (CAD). In a European registry of 11,000 stable angina patients, 65% of women and 32% of men had no obstructive CAD (<50% stenosis); however, multiple other studies have demonstrated only 30% of patients have significant obstructive epicardial…
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