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Research Area(s) / Expertise: Job title: Professor
Frédéric Sacher was trained in electrophysiology in Bordeaux. During his fellowship in Boston at Brigham and Women’s Hospital (Harvard Medical School) with W.G. Stevenson, he was trained to ventricular tachycardia ablation. In 2007, he came back to Bordeaux with a praticien hospitalier position in Michel Haissaguerre’s department. Since 2017, he has a professor position. Dr Sacher routinely… View more
Author(s): Ilan Goldenberg Added: 2 years ago
In this video, Dr Ilan Goldenberg (University of Rochester Medical Center, Rochester, NY, US) discusses the potential risk of cardiac events in women with congenital long QT syndrome (LQTS) associated with contraceptive use in this cohort. Questions: 1. Please remind us of the aim, study design and endpoints? 2. What were your key findings? 3. How should your findings impact practice and… View more
Author(s): Giulio Conte , Ulrich Schotten , Angelo Auricchio Added: 3 years ago
The Risk of Atrial Arrhythmias in Inherited Primary Arrhythmia Syndromes The inherited primary arrhythmia syndromes (IPAS) are a heterogeneous group of diseases caused by mutations in genes encoding for cardiac ion channels. People affected by one of these inherited diseases have no overt structural cardiac abnormalities but are at higher risk of sudden cardiac death due to the occurrence of… View more
Added: 3 years ago
WEARABLE CARDIOVERTER DEFIBRILLATORS PROVE TO BE SAFE FOR PEDIATRIC PATIENTS AT RISK FOR SUDDEN CARDIAC ARREST Largest study of its kind finds device effective in detecting and treating life-threatening arrhythmias CHICAGO, May 11, 2017 – A new study shows that the use of a wearable cardioverter defibrillator (WCD) is safe and effective in treating ventricular arrhythmias for pediatric patients… View more
Author(s): Shubhayan Sanatani Added: 3 years ago
In children and young adults, sudden cardiac death (SCD) occurs in approximately 1-2 per 100,000 population.1,2 While the overwhelming majority of occurrences of SCD occur in the adult population and are due to ischemic heart disease, very few cases in a pediatric population are. Pediatric SCD is a relatively uncommon occurrence whose underlying etiology often remains elusive. A long list of… View more
Author(s): Rachel Lampert , Michael Ackerman , Sharlene Day Added: 1 year ago
ACC.23/WCC—We are joined onsite by principal investigator Dr Rachel Lampert (Yale School of Medicine, US), Dr Sharlene Day (Penn Medicine, US) and Dr Michael Ackerman (Mayo Clinic, US) to discuss the late-breaking findings from the LIVE-HCM Study. In this trial, investigators aimed to determine the effects of lifestyle and exercise on the well-being of patients with hypertrophic cardiomyopathy … View more
Author(s): Demosthenes G Katritsis , Bernard J Gersh , A John Camm Added: 3 years ago
Sudden cardiac death (SCD) is usually defined as death due to cardiac causes occurring within 1 hour of the onset of symptoms. Unexplained sudden death occurring in an individual older than 1 year of age is known as 'sudden unexplained death syndrome'. Unexplained sudden death occurring in an individual younger than 1 year of age is known as 'sudden unexplained death in infancy'. SCD with… View more
Author(s): A John Camm , Bernard J Gersh , Demosthenes G Katritsis Added: 3 years ago
Inherited arrhythmias comprise a group of disorders with inherited susceptibility to arrhythmias and conduction disturbances due to mutations in genes mainly encoding the Na+, and K+ channels, and other arrhythmogenic mechanisms such as those linked to Ca++ transport (Table 1).1 The majority of heritable cardiomyopathies and channelopathies are associated with disease-susceptibility genes… View more
Author(s): Nabil El-Sherif , Gioia Turitto , Mohamed Boutjdir Added: 3 years ago
Since its initial description by Jervell and Lange-Nielsen in 1957,1 congenital long QT syndrome (LQTS) has been the most investigated cardiac ion channelopathy. A prolonged QT interval on the surface ECG is a surrogate measure of prolonged ventricular action potential duration (APD). Congenital as well as acquired alterations in certain cardiac ion channels can affect their currents in such a… View more