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Author(s): Constantinos O’Mahony , Saidi Mohiddin , Charles Knight Added: 3 years ago
Hypertrophic cardiomyopathy (HCM) is a genetic disorder of cardiac muscle with a heterogeneous clinical course.1 The disease is clinically characterised by left ventricular hypertrophy (LVH), which is typically asymmetric, and a subgroup of patients have left ventricular outflow tract obstruction (LVOTO) caused by systolic anterior motion (SAM) of the mitral valve leaflet(s).2,3 LVOTO is often… View more
Author(s): Morton J Kern Added: 4 years ago
Prof Morton Kern (VA Long Beach Health Care System, Long Beach, CA, US) discusses whether Quantitative flow ratio (QFR) will ever replace fractional-flow reserve (FFR). Questions: 1. What is QFR and why is it needed? 2. Where is QFR being used and what data supports it? 3. Will QFR replace FFR? 4. How does it compare to resting indices like iFR? 5. What is needed to validate QFR as a serious… View more
Author(s): Roberto Scarsini , Dimitrios Terentes-Printzios , Giovanni Luigi De Maria , et al Added: 3 years ago
Acute coronary syndromes (ACS) encompass a wide spectrum of clinical presentations that range from ST-elevation MI (STEMI) to non-ST-elevation MI and unstable angina. These conditions are life threatening and remain a source of high morbidity and mortality. Unfortunately, despite major accomplishments worldwide in timely reperfusion with percutaneous coronary intervention (PCI), an important… View more
Author(s): Jonathon A Leipsic , Jonathan Weir-McCall , Philipp Blanke Added: 3 years ago
Coronary CTA has rapidly gone from a test with potential to be considered a first-line test for patients with stable chest pain.1 It provides robust ability to exclude atherosclerosis and coronary artery stenosis and more recently has been shown to inform and guide clinical treatment making in a fashion that enables a reduction in myocardial infarction when compared to traditional stress testing… View more
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Dr Justin Davies is a Senior Research Fellow and Consultant Cardiologist at Imperial College London. He also completed his undergraduate training and continued on to complete his PhD at Imperial after being awarded a British Heart Foundation research fellowship. Now a leading clinical academic in the field of interventional cardiology, Dr Davies has pioneered several new techniques, including… View more
Author(s): Javier Escaned , Justin E Davies Start date: Mar 23, 2017
During the recent Scientific Sessions of the American College of Cardiology (ACC 2017) the results of two large studies in coronary physiology, DEFINE FLAIR and iFR SWEDEHEART, were presented. Together, the population of these two studies exceed that of all available trials on FFR. The conclusions are highly relevant to understand the present and future of physiological guidance of coronary… View more