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The Bifurcation Center

Your center for bifurcation knowledge

Coronary bifurcations present complex challenges for interventional cardiologists.
The Bifurcation Center brings clarity, evidence and expert understanding to every step of bifurcation PCI.

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Welcome to The Bifurcation Center

Join Section Advisor: Prof Goran Stankovic!

Watch the introduction video to hear from Prof Stankovic and unlock all the resources waiting for you.


Discover:

  • Expert interviews
  • Step-by-step procedural guides
  • Unique inside-the-vessel footage
  • The latest congress highlights
  • Up-to-date clinical evidence

Bifurcation Techniques

Provisional Stenting

Provisional stenting is a treatment philosophy – rather than a technique – that meets the objective of bifurcation lesion treatment with a single stent whenever possible. 
 

Guidance from the 16th EBC consensus1

  • Single stent, less metal
  • Keep it simple and safe
  • Stepwise approach emphasising versatility based upon bifurcation lesion complexity

1 Albiero R, Burzotta F, Lassen JF, et al. Treatment of coronary bifurcation lesions, part I: implanting the first stent in the provisional pathway. The 16th expert consensus document of the European Bifurcation Club. EuroIntervention 2022;18:e362–76.
 

Explore more bifurcation techniques:

T and TAP in Practice | Culotte Overview | DK Crush | Visible Heart Lab

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T and TAP in Practice

The T and small protrusion (TAP) technique is a modification of provisional T-stenting aimed at optimising implantation of a second stent in bifurcated coronary lesions treated using the provisional pathway.1
The stent from the SB is intentionally positioned with a small (1–2 mm) protrusion in the MV, to fully cover the ostium area and is deployed simultaneously with a balloon positioned in the MV.1
TAP- stenting was developed and reported by Burzotta et al in 2007, with the aim of improving the T-stenting technique to ensure full ostial coverage, where bifurcation geometry prevents perfect alignment of stents and to provide a strategy to facilitate final KBI. 

1 Burzotta F, Džavík V, Ferenc M, et al. Technical aspects of the T And small Protrusion (TAP) technique. EuroIntervention 2015;11 Suppl V:V91-5.
 

Explore more bifurcation techniques:

Provisional Stenting | Culotte Overview | DK Crush | Visible Heart Lab

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Culotte Overview

Culotte may be practiced in both intentional double-stenting procedures and in provisional procedures when a second stent is required. The main limitation of Culotte stenting is the possible presence of major mismatch between the size of the proximal MV and SB. Thus, two aspects are recognised as critical, the stent platform selection and the application of POT during the procedural flow.1

Culotte

  • Is associated with high procedural success and relatively low risk of angiographic restenosis
  • In bifurcations with narrow angles
  • In bifurcations with similar diameters

1Lassen JF, Holm NR, Banning A, et al. Percutaneous coronary intervention for coronary bifurcation disease: 11th consensus document from the European Bifurcation Club. EuroIntervention 2016;12:38–46.

Explore more bifurcation techniques:

Provisional Stenting | T and TAP in Practice | DK Crush | Visible Heart Lab

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DK Crush

This technique is a true intentional upfront two stent approach in the treatment of complex bifurcation lesions (CBL) with extensive side branch disease. It will always end with two stents and maximum metallic coverage of the bifurcation.


DK Crush belongs to the “S” family of the MADS-2 classification of bifurcation stenting techniques and is always finalised with 2 stents in the bifurcation. The first stent is implanted in the side branch.    



Lassen JF, Albiero R, Johnson TW, et al. Treatment of coronary bifurcation lesions, part II: implanting two stents. The 16th expert consensus document of the European Bifurcation Club. EuroIntervention 2022;18:457–70.

 

Explore more bifurcation techniques:

Provisional Stenting | T and TAP in Practice | Culotte Overview | Visible Heart Lab

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Visible Heart Lab (University of Minneapolis) / Medtronic Collaboration
  • Exclusive collaboration with Medtronic and ongoing partnerships with the world's leading bifurcation clubs including EBC, JBC, KBC and LATAM, and now emerging US
  • Development of educational materials leveraging technique and our unique stent portfolio characteristics (Bifurcation Exploration, Speaker decks and Visible Heart footage)
  • Unparalleled multi-modality imaging gives ICs never before seen looks into techniques they perform in their daily practice 

 

Explore more bifurcation techniques:

Provisional Stenting | T and TAP in Practice | Culotte Overview | DK Crush

Key Trials

EBC Consensus Documents
Drug-Coated Balloon Publications
Drug-coated balloon-based treatment of left main true bifurcation lesion 

Her AY, Kim TH, Shin ES, et al. Catheter Cardiovasc Interv 2025;105:1024–31.

A comparison of a drug coated balloon with drug eluting stent strategy for treating coronary bifurcation lesions 

Corballis N, Merinopoulos I, Bhalraam U, et al. Catheter Cardiovasc Interv 2026;107:3–14.

Bifurcation PCI with a hybrid strategy with drug- eluting balloons versus a stepwise provisional two- stent strategy: rationale and design of the hybrid DEB study  

Dillen DMM, Vlaar PJ, Vermeer AJE, et al. Am Heart J 2023;266:168–75.

Drug-coated balloons for coronary bifurcation lesions 

Fezzi S, Scheller B, Rissanen TT, et al. EuroIntervention 2025;21:e1177–97.

Drug-coated balloon treatment in coronary artery disease: recommendations from an Asia-Pacific Consensus Group 

Her AY, Shin ES, Bang LH, et al. Cardiol J 2021;28:136–49.

 
Explore more publications:
EBC Consensus Documents | Left Main Bifurcation Publications
Drug-Coated Balloon Publications
Drug coated balloons and their role in bifurcation coronary angioplasty: appraisal of the current evidence and future directions 

Rathore S, Tehrani S, Prvulovic D, et al. Expert Rev Med Devices 2020;17:1021–33.

Drug-coated balloons for de novo non-aorto-ostial and coronary bifurcation lesions: a systematic review and meta-analysis 

Mariscal ES, Slotwiner A, Karam B, et al. J Soc Cardiovasc Angiogr Interv 2025;4(12):103944.

Drug-coated balloons versus non-coated balloons for side branch treatment in bifurcation lesions: a systematic review and meta-analysis 

Rocchetti M, Tua L, Cereda A, et al. Catheter Cardiovasc Interv 2025;106:530–9.

Application of drug-coated balloons in complex high risk and indicated percutaneous coronary interventions 

Somsen YBO, Rissanen TT, Hoek R, et al. Catheter Cardiovasc Interv 2025;105:494–516.

 
Explore more publications:
EBC Consensus Documents | Left Main Bifurcation Publications
Positioning Statements Publications
Provisional and Side Branch Protection Publications
Provisional and Side Branch Protection Publications
Multimodal comparisons of results achieved by different side branch ballooning techniques for bifurcation provisional stenting 

Bianchini F, Cangemi S, DeVos A, et al. Circ Cardiovasc Interv 2023;16:e012908.

Proximal optimization technique and percutaneous coronary intervention for left main disease: POTENTIAL-LM 

Volet C, Puricel S, Cook ST, et al. Catheter Cardiovasc Interv 2024;103:417–24.

Szabo 2-stent technique for coronary bifurcation lesions: procedural and short-term outcomes 

Yang H, Qian J, Huang Z, Ge J. BMC Cardiovasc Disord 2020;20:325.

Imaging-Guided PCI Publications
OCT or angiography guidance for PCI in complex bifurcation lesions 

Holm NR, Andreasen LD, Neghabat O, et al. N Engl J Med 2023;389:1477–87.

OCT-guided vs angiography-guided coronary stent implantation in complex lesions: an ILUMIEN IV substudy 

Ali ZA, Landmesser U, Maehara A, et al. J Am Coll Cardiol 2024;84:368–78.

Guiding intervention for complex coronary lesions by optical coherence tomography or intravascular ultrasound 

Kang DY, Ahn JM, Yun SC, et al. J Am Coll Cardiol 2024;83:401–13.

Unintended deformation of stents during bifurcation PCI: an OCTOBER trial substudy 

Andreasen LN, Neghabat O, Laanmets P, et al. JACC Cardiovasc Interv 2024;17:1106–15.

Imaging-Guided PCI Publications
Computational, 3D and Physiology Publications
Virtual 2-stent bifurcation percutaneous coronary intervention using the fractional flow reserve computed tomography planner 

Ohashi H, Zivelonghi C, Seki R, et al. JACC Cardiovasc Interv 2023;16:863–4.

Impact of bifurcation lesions on outcomes after FFR-guided PCI or CABG 

Burzotta F, Louvard Y, Lassen JF, et al. Circ Cardiovasc Interv 2025;18:e014610.

Risk Registry Prognostic Publications