Does renal function have incremental predictive value of stroke in atrial fibrillation?

Yukihito Higashi

It is well known that both atrial fibrillation (AF) and chronic kidney disease (CKD) are respectively independent predictors of stroke and systemic thromboembolism. A number of epidemiological and observational studies have shown that there are close relationships between AF and CKD [1–3]. Indeed, the prevalence of AF increases from non-CKD to CKD stages of 1 to 2, 3 and 4 to 5 by 1.0%, 2.8%, 2.7%, and 4.2%, respectively [1], and the prevalence is 7% to 27% in patients with end-stage renal disease who are undergoing hemodialysis therapy [2].

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Higashi Y. Int J Cardiol. 29 August, 2018. pii: S0167-5273(18)34620-5. Epub ahead of print.