ICR

Thrombus Embolisation: Prevention is Better than Cure

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This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly.

Over the last few decades, primary percutaneous coronary intervention (PCI) has revolutionised the treatment of ST-elevation myocardial infarction (STEMI) with rapid recanalisation of the infarct-related epicardial vessel, resulting in smaller infarct size and a substantial reduction in adverse clinical endpoints.1,2 However, suboptimal myocardial reperfusion is documented to occur in a relatively large proportion of patients undergoing primary PCI for STEMI, despite optimal restoration of epicardial flow, with unfavourable s

Coronary Artery Vasospasm Induced by 5-fluorouracil: Proposed Mechanisms, Existing Management Options and Future Directions

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This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly.

Cardiovascular disease is the leading cause of morbidity and mortality worldwide.1 The WHO estimates that 17 million people die each year of cardiovascular disease, about 30% of all deaths.2 Cancer is the second leading cause of death globally and is associated with 9 million deaths each year.3 According to the WHO, the incidence of cancer is expected to rise by about 70% over the next 20 years.4

How to Diagnose and Manage Angina Without Obstructive Coronary Artery Disease: Lessons from the British Heart Foundation CorMicA Trial

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This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly.

Ischaemic heart disease persists as the leading global cause of death and lost life years in adults.1 Angina is a common clinical presentation of ischaemic heart disease related to a supply:demand mismatch of myocardial blood flow, typically provoked by exertion or stress. Invasive coronary angiography is the reference test for angina and identifies obstructive coronary artery disease (CAD) as a cause for symptoms.

Outcomes After Percutaneous Coronary Intervention in Women: Are There Differences When Compared with Men?

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This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly.

Cardiovascular disease is a major cause of morbidity and is the leading cause of death in women and men in Western societies.1 Despite the major advances seen in the field of interventional cardiology and pharmacotherapy, which have translated into better outcomes, a disparity is evident in the clinical outcomes between men and women.

Long-term Transcatheter Aortic Valve Durability

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This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly.

Aortic stenosis (AS) is one of the most common valvular diseases in developed countries and its prevalence is projected to increase over the next decade as the population ages.1,2 Transcatheter aortic valve implantation (TAVI) is an established alternative to surgery for treatment of patients with symptomatic, severe AS.3