Among the many contributions for Arrhythmia & Electrophysiology Review (AER) – Volume 2 Issue 2, Ethan R Ellis and Mark E Josephson discuss the proposed mechanisms of tachycardia-induced cardiomyopathy, the causative tachyarrhythmias and their treatment, outcomes for patients diagnosed with TIC, and future directions for research and clinical care. Elsewhere, following the publication of the recent EHRA Practical Guide on the Use of New Oral Anticoagulants in Patients with Non-valvular Atrial Fibrillation, this issue includes a comprehensive summary of the guidelines, reviewed Paulus Kirchhof, one of the co-authors of the original work.