Paediatric HF is a complex clinical syndrome resulting from diverse primary and secondary causes and shared pathways of disease progression, correlating with substantial mortality, morbidity and cost.Load more
Paediatric HF is a complex clinical syndrome resulting from diverse primary and secondary causes and shared pathways of disease progression, correlating with substantial mortality, morbidity and cost.
Current management includes stabilisation with intravenous inotropes/vasopressors, mechanical ventilation, treatment of arrhythmia, and progression to mechanical support. Early identification and treatment of patients who are in the early stages is critical to prevent progression to end-stage heart failure.
Ventricular assist devices (VADs) have taken an increasingly important role in the management of advanced heart failure in children. The predominant role of these devices has been as a bridge to heart transplantation, and excellent results are currently achieved for most children with cardiomyopathies.Load Less
Paediatric Heart Failure - Selected Papers
Incidence and echocardiographic predictors of early postoperative right ventricular dysfunction following left ventricular assist implantation in paediatric patientsRedlin M, Miera O, Habazettl H, et al. Interact Cardiovasc Thorac Surg 2017;25:881–91.
Second annual Pediatric Interagency Registry for Mechanical Circulatory Support (Pedimacs) report: Pre-implant characteristics and outcomesBlume ED, VanderPluym C, Lorts A, et al. J Heart Lung Transplant 2018;37:34–45.
Fibrosis and Fibrotic Gene Expression in Pediatric and Adult Patients With Idiopathic Dilated CardiomyopathyWoulfe KC, Siomos AK, Nguyen H, et al. J Card Fail 2017;23:314–24.
Patel MD, Mohan J, Schneider C, et al. JCI Insight 2017;2:94382.